Phenotypes associated with this allele

• Allele Symbol: Kat14^{Gt(OST388291)Lex}
• Allele Name: gene trap OST388291, Lexicon Genetics
• Allele ID: MGI:3836392
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Kat14^Gt(OST388291)Lex/Kat14^Gt(OST388291)Lex	involves: 129S5/SvEvBrd * C57BL/6	MGI:3836419

Genotype
MGI:3836419

hm1

• Allelic Composition: Kat14^{Gt(OST388291)Lex}/Kat14^{Gt(OST388291)Lex}
• Genetic Background: involves: 129S5/SvEvBrd * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality, complete penetrance ( J:145720 )

• mice die between E8.5 and E11

cellular

abnormal cell cycle ( J:145720 )

• progression through G1 and G2/M phases is disrupted

increased apoptosis ( J:145720 )

• mice exhibit increased apoptosis especially in the neuroectoderm unlike in wild-type mice

increased embryonic neuroepithelium apoptosis ( J:145720 )

• mice exhibit increased apoptosis especially in the neuroectoderm unlike in wild-type mice

nervous system

increased embryonic neuroepithelium apoptosis ( J:145720 )

• mice exhibit increased apoptosis especially in the neuroectoderm unlike in wild-type mice

embryo

decreased embryo size ( J:145720 )

• at E7.5 and E8.5

growth/size/body

decreased embryo size ( J:145720 )

• at E7.5 and E8.5