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Gene Expression Data
Assay Details
Assay
Reference: J:121808 Tamura M, et al., Members of a novel gene family, Gsdm, are expressed exclusively in the epithelium of the skin and gastrointestinal tract in a highly tissue-specific manner. Genomics. 2007 May;89(5):618-29
Assay type: RNA in situ
MGI Accession ID: MGI:3826363
Gene symbol: Gsdmc4
Gene name: gasdermin C4
Probe: Gsdmc4 cDNA1
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Assay notes: Due to high similarity among the clustering genes, the Gsdmc4 probe cross-reacted with the transcripts of the entire Gsdmc cluster; Gsdmc1-4 have been annotated. There were some inconsistencies in text and the panel assignments in the figure legend.
Results
Specimen 6B: postnatal adult (more )
Structure Level Pattern Image Note
TS28: stomach cardiac region Present Regionally restricted 6B Expressing cells contact the epithelial basal layer.
Specimen 6D: postnatal adult (more )
Note: Double labeled: purple - Gsdmc cluster; orange - Gsdma cluster.
Structure Level Pattern Image Note
TS28: stomach glandular region mucosa Present Regionally restricted 6D Expression is in the middle of the gastric mucosa.
Specimen 6E: postnatal adult (more )
Structure Level Pattern Image Note
TS28: small intestine crypt of lieberkuhn Present Regionally restricted 6E Expression is in the middle to the upper crypt.
Specimen 6F: postnatal adult (more )
Note: Double labeled: purple - Gsdmc cluster; orange - Gsdma cluster.
Structure Level Pattern Image Note
TS28: small intestine crypt of lieberkuhn Present Regionally restricted 6F Expression is in the middle to the upper crypt.
Specimen 6G: postnatal adult (more )
Structure Level Pattern Image Note
TS28: small intestine crypt of lieberkuhn Present Regionally restricted 6G Expression is in the middle to the upper crypt.
Specimen 6I: postnatal adult (more )
Note: Double labeled: orange - Gsdmc cluster; purple - Gsdmd
Structure Level Pattern Image Note
TS28: small intestine Present 6I
Specimen 6J: postnatal adult (more )
Structure Level Pattern Image Note
TS28: colon Present Regionally restricted 6J Expression is in the middle to the upper crypt.
Specimen 6L: postnatal adult (more )
Structure Level Pattern Image Note
TS28: colon Present Regionally restricted 6L Expression is in the middle to the upper crypt.
Specimen 6M: postnatal adult (more )
Note: Double labeled: purple - Gsdmc cluster; orange - Pcna
Structure Level Pattern Image Note
TS28: stomach cardiac region Present Regionally restricted 6M Expression is in the differentiating epithelium.
Specimen 6N: postnatal adult (more )
Note: Double labeled: purple - Gsdmc cluster; orange - Pcna
Structure Level Pattern Image Note
TS28: stomach fundus Present Regionally restricted 6N Expression is in the differentiating epithelium.
Specimen 6O: postnatal adult (more )
Note: Double labeled: purple - Gsdmc cluster; orange - Pcna
Structure Level Pattern Image Note
TS28: cecum Present Regionally restricted 6O Expression is in the differentiating epithelium.
Specimen Not Shown: postnatal adult (more )
Structure Level Pattern Image Note
TS28: esophagus Strong Regionally restricted Expression is in the fundus linked to the esophageal-cardiac junction. Low expression in the remaining fundus.
TS28: stomach fundus Strong Regionally restricted Expression is in the fundus linked to the esophageal-cardiac junction. Low expression in the remaining fundus.
TS28: stomach pyloric region Weak
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory