Summary | Transgene origin | Transgene description | Find Mice (IMSR) | References

Symbol:	Tg(Igk*G)G07Dgs
Name:	transgene insertion G07, David G Schatz
MGI ID:	MGI:3811466
Synonyms:	TgG
Transgene:	Tg(Igk*G)G07Dgs  Location: unknown
Alliance:	Tg(Igk*G)G07Dgs page

Strain of Origin:

C57BL/6 and SJL

Transgene Type:    Transgenic (Inserted expressed sequence) Mutation:    Insertion   Tg(Igk*G)G07Dgs expresses 1 gene Transgene expresses: Organism Expressed Gene Note mouse Igk (MGI:96494)   Mutation details: Vk167/PEPS is an Igk transgene with a truncated region upstream of the promoter. The Igk (immunoglobulin kappa) sequence was further modified through the insertion, near the 3' end of the variable region of Igk, of 5 tandem repeats of a 20-bp adenine/thymine (A/T) fragment in the same orientation as the insert in the TgA line but includes a single guanine:cytosine (G:C) base pair in the central repeat. In this "TgG" line, the cytosine was placed on the 3'->5' strand of the DNA. (J:139793)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available

Original:	J:139793 Unniraman S, et al., Strand-biased spreading of mutations during somatic hypermutation. Science. 2007 Aug 31;317(5842):1227-30
All:	1 reference(s)