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Gene Expression Data
Assay Details
Assay
Reference: J:108509 Blaess S, et al., Sonic hedgehog regulates Gli activator and repressor functions with spatial and temporal precision in the mid/hindbrain region. Development. 2006 May;133(9):1799-809
Assay type: Immunohistochemistry
MGI Accession ID: MGI:3810803
Gene symbol: Th
Gene name: tyrosine hydroxylase
Antibody: anti-TH
Results
Specimen 2A: embryonic day 18.5 (more )
Note: This is a sagittal section.
Structure Level Pattern Image Note
TS26: hindbrain Present Regionally restricted 2A Expression is present in dopaminergic neurons.
Specimen 2C: embryonic day 18.5; Smotm2Amc/Smotm2Amc, En1tm2(cre)Wrst/En1+ (more )
Note: Conditional mutant. This is a sagittal section.
Structure Level Pattern Image Note
TS26: hindbrain Present Regionally restricted 2C Expression is present in dopaminergic neurons; the number of these neurons is greatly reduced compared to the number seen in wild type.
TS26: brainstem Present Regionally restricted 2C Expression is present in dopaminergic neurons in the locus coeruleus.
Specimen 2E: embryonic day 18.5; Smotm1Amc/Smotm2Amc, Tg(Nes-cre)1Kln/0 (more )
Note: Conditional mutant. This is a sagittal section.
Structure Level Pattern Image Note
TS26: hindbrain Present Regionally restricted 2E Expression is present in dopaminergic neurons; induction of these neurons is not affected in the mutant.
Specimen 2G: embryonic day 18.5; Gli2tm6Alj/Gli2tm6Alj, En1tm2(cre)Wrst/En1+ (more )
Note: Conditional mutant. This is a sagittal section.
Structure Level Pattern Image Note
TS26: hindbrain Present Regionally restricted 2G Expression is present in dopaminergic neurons; the number of these neurons is greatly reduced compared to the number seen in wild type.
Specimen Not shown: embryonic day 18.5; Shhtm1Chg/Shhtm1Chg (more )
Structure Level Pattern Image Note
TS26: hindbrain Absent No dopaminergic neurons are present in the mutant.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory