Summary | Mutation origin | Mutation description | Expression | Recombinase activity | Phenotypes | Find Mice (IMSR) | References

Symbol:	Wt1tm1(EGFP/cre)Wtp
Name:	WT1 transcription factor; targeted mutation 1, William T Pu
MGI ID:	MGI:3801681
Synonyms:	Wt1GFPCre
Gene:	Wt1  Location: Chr2:104956874-105003959 bp, + strand  Genetic Position: Chr2, 55.06 cM, cytoband E
Alliance:	Wt1tm1(EGFP/cre)Wtp page

Germline Transmission:	Earliest citation of germline transmission: J:137426
Parent Cell Line:	J1 (ES Cell)
Strain of Origin:	129S4/SvJae

Allele Type:    Targeted (Recombinase) Mutations:    Insertion, Intragenic deletion   Wt1tm1(EGFP/cre)Wtp expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Wt1 (MGI:98968)   Mutation details: Exon 1 was replaced with an EGFP-cre derived from pBS592 and an frt-flanked neo cassette. Germ line, flp-mediated recombination was used to remove the neo cassette. (J:137426)

Activity:	Tissue activity of this recombinase allele
Driver:	Wt1 (mouse) Summary of all recombinase alleles driven by Wt1. Comparative matrix view of recombinase activities Alliance mouse Wt1 gene page

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:

52027 assay results 2 RNA-Seq or microarray experiment(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Wt1 Mutation:	34 strains or lines available

Original:	J:137426 Zhou B, et al., Epicardial progenitors contribute to the cardiomyocyte lineage in the developing heart. Nature. 2008 Jul 3;454(7200):109-13
All:	47 reference(s)