Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Ccl25tm1.1Mal
Name:	C-C motif chemokine ligand 25; targeted mutation 1.1, Bernard Malissen
MGI ID:	MGI:3797365
Synonyms:	Ccl25tm1Mal
Gene:	Ccl25  Location: Chr8:4375210-4410020 bp, + strand  Genetic Position: Chr8, 2.01 cM
Alliance:	Ccl25tm1.1Mal page

Germline Transmission:	Earliest citation of germline transmission: J:136944
Parent Cell Line:	CK35 (ES Cell)
Strain of Origin:	129S2/SvPas

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Part of exon 2 (including the translation initiation site) and all of exons 3 and 4 were replaced with a floxed neomycin resistance gene cassette. The neo cassette was removed through subsequent germline, cre-mediated recombination. (J:136944)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Ccl25 Mutation:	39 strains or lines available

Original:	J:136944 Wurbel MA, et al., Impaired accumulation of antigen-specific CD8 lymphocytes in chemokine CCL25-deficient intestinal epithelium and lamina propria. J Immunol. 2007 Jun 15;178(12):7598-606
All:	4 reference(s)