Arid1atm1.2Zhwa
Targeted Allele Detail
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| Symbol: |
Arid1atm1.2Zhwa |
| Name: |
AT-rich interaction domain 1A; targeted mutation 1.2, Zhong Wang |
| MGI ID: |
MGI:3796520 |
| Synonyms: |
BAF250a- |
| Gene: |
Arid1a Location: Chr4:133406319-133484080 bp, - strand Genetic Position: Chr4, 66.25 cM
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| Alliance: |
Arid1atm1.2Zhwa page
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| Germline Transmission: |
Earliest citation of germline transmission:
J:134633
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| Parent Cell Line: |
E14 (ES Cell)
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| Strain of Origin: |
129P2/OlaHsd
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| Allele Type: |
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Targeted (Null/knockout) |
| Mutation: |
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Intragenic deletion
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Mutation details: An frt-flanked betageo cassette with a 3' loxP site and a 5' SV40-polyA tail was inserted downstream of exon 8 and an additional loxP site was inserted upstream of exon 8. Transient flp expression in ES cells was used to remove the betageo cassette and leave exon 8 floxed. Cre expression in germline cells removed exon 8 and created a null allele. No gene product was detected by PCR in homozygous null embryos.
(J:134633)
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Arid1a Mutation: |
179 strains or lines available
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| Original: |
J:134633 Gao X, et al., ES cell pluripotency and germ-layer formation require the SWI/SNF chromatin remodeling component BAF250a. Proc Natl Acad Sci U S A. 2008 May 6;105(18):6656-61 |
| All: |
1 reference(s) |
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Analysis Tools
