About   Help   FAQ
Tg(PON1)1Lus
Transgene Detail
Summary
Symbol: Tg(PON1)1Lus
Name: transgene insertion 1, Aldons J Lusis
MGI ID: MGI:3795158
Synonyms: PON1 Tg
Transgene: Tg(PON1)1Lus  Location: unknown  
Alliance: Tg(PON1)1Lus page
Transgene
origin
Strain of Origin:  C57BL/6J
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(PON1)1Lus expresses 1 gene
 
Mutation detailsA 45-kb fragment containing the intact human PON1 gene with 10 kb of 5'-flanking and 10 kb of 3'-flanking sequences was used for the production of Tg mice. This transgenic line carried ~3 copies of the transgene, as determined by Southern blot analysis. (J:103311)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:103311 Tward A, et al., Decreased atherosclerotic lesion formation in human serum paraoxonase transgenic mice. Circulation. 2002 Jul 23;106(4):484-90
All:  7 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
03/25/2025
MGI 6.24
The Jackson Laboratory