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Gene Expression Data
Assay Details
Assay
Reference: J:129685 Amendola E, et al., A mouse model demonstrates a multigenic origin of congenital hypothyroidism. Endocrinology. 2005 Dec;146(12):5038-47
Assay type: RT-PCR
MGI Accession ID: MGI:3793956
Gene symbol: Dio1
Gene name: deiodinase, iodothyronine, type I
Probe: Dio1-pC, Dio1-pD
Probe preparation: labelled with SYBR green
Results Image: 6_Dio1
 Sample Information Bands Other Sample Information
Lane AgeStructure Size Not Specified Amount Genetic BackgroundMutant Allele(s)Sex
Tg B6 Lane not used in this assay
Tg DHTP/B6 Lane not used in this assay
Dio1 B6 E18.5 TS26: thyroid gland Present 4 µg; total RNA C57BL/6J Not Specified
Dio1 DHTP/B6 E18.5 TS26: thyroid gland Weak (a) 4 µg; total RNA B6.129-Pax8tm1Pgr Nkx2-1tm1Shk/Rdl Nkx2-1tm1Shk/Nkx2-1+, Pax8tm1Pgr/Pax8+Not Specified
TshR B6 Lane not used in this assay
TshR DHTP/B6 Lane not used in this assay
TPO B6 Lane not used in this assay
TPO DHTP/B6 Lane not used in this assay
Tg B6/Sv-F1 Lane not used in this assay
Tg DHTP/B6/Sv-F1 Lane not used in this assay
Dio1 B6/Sv-F1 E18.5 TS26: thyroid gland Present 4 µg; total RNA involves: 129S2/SvPasCrl * C57BL/6J Not Specified
Dio1 DHTP/B6/Sv-F1 E18.5 TS26: thyroid gland Present 4 µg; total RNA involves: 129S2/SvPasCrl * C57BL/6J Nkx2-1tm1Shk/Nkx2-1+, Pax8tm1Pgr/Pax8+Not Specified
TshR B6/Sv-F1 Lane not used in this assay
TshR DHTP/B6/Sv-F1 Lane not used in this assay
TPO B6/Sv-F1 Lane not used in this assay
TPO DHTP/B6/Sv-F1 Lane not used in this assay
Notes:
(a) Levels were significantly reduced compared with wild type samples.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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