Gene Expression Data
Assay Details
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Assay
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Reference:
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J:129577
Kang LI, et al., Deletion of JAM-A causes morphological defects in the corneal epithelium. Int J Biochem Cell Biol. 2007;39(3):576-85
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:3793769
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Gene symbol:
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F11r
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Gene name:
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F11 receptor
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Antibody:
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anti-JAM-A
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Detection system:
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Secondary antibody coupled to Alexa Fluor 568
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Assay notes:
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Specimens were fixed in 1:1 acetone:methanol.
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Results
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Specimen
1A:
embryonic day 12.5
(more  )
Specimen
1A:
(close  )
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Genetic Background:
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C57BL/6NHsd
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Age:
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embryonic day 12.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Other - See Notes
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS20: hyaloid vascular plexus |
Present |
Regionally restricted |
1A
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Expression in blood vessels of the tunica vasculosa.
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Specimen
1B:
embryonic day 14.5
(more )
Specimen
1B:
(close )
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Genetic Background:
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C57BL/6NHsd
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Age:
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embryonic day 14.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Other - See Notes
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS22: cornea epithelium |
Strong |
Regionally restricted |
1B
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Strong expression in the cell membrane of the presumptive corneal epithelium.
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| TS22: lens epithelium |
Weak |
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1B
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Lower levels in the lens epithelium and fibers.
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| TS22: lens fiber |
Weak |
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1B
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Lower levels in the lens epithelium and fibers.
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Specimen
1C:
embryonic day 16.5
(more )
Specimen
1C:
(close )
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Genetic Background:
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C57BL/6NHsd
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Age:
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embryonic day 16.5
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Other - See Notes
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS24: conjunctival sac |
Strong |
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1C
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Strong expression in the corneal epithelium, conjunctiva epithelium and eyelid epithelium.
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| TS24: cornea epithelium |
Strong |
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1C
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Strong expression in the corneal epithelium, conjunctiva epithelium and eyelid epithelium.
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| TS24: eyelid epithelium |
Strong |
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1C
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Strong expression in the corneal epithelium, conjunctiva epithelium and eyelid epithelium.
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Specimen
1D:
postnatal newborn
(more )
Specimen
1D:
(close )
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Genetic Background:
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C57BL/6NHsd
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Age:
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postnatal newborn
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Other - See Notes
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Embedding:
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Cryosection
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Specimen
1E:
postnatal adult
(more )
Specimen
1E:
(close )
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Genetic Background:
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C57BL/6NHsd
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Other - See Notes
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Embedding:
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Cryosection
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Specimen
not shown:
(close )
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Genetic Background:
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involves: 129P2/OlaHsd * C57BL/6
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Mutant Allele(s):
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F11rGt(KST235)Byg/F11rGt(KST235)Byg
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Other - See Notes
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: eye |
Absent |
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Specimen
2A:
postnatal adult
(more )
Specimen
2A:
(close )
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Genetic Background:
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Not Specified
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Other - See Notes
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Embedding:
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Cryosection
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Specimen
2B:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * NMRI
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Mutant Allele(s):
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Pax6tm1Pgr/Pax6tm1Pgr
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Other - See Notes
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: lens epithelium |
Present |
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2B
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Expression in lens epithelial and fiber cells, slightly weaker overall than in wild type mice.
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| TS28: lens fiber |
Present |
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2B
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Expression in lens epithelial and fiber cells, slightly weaker overall than in wild type mice.
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Specimen
2C:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ * NMRI
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Mutant Allele(s):
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Pax6tm1Pgr/Pax6tm1Pgr
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Other - See Notes
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: cornea epithelium |
Present |
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2C
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Expression in the corneal epithelium, not notably altered compared to wild type mice.
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