Summary | Transgene origin | Transgene description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Tg(Ins2-E3*309)5Dvs
Name:	transgene insertion 5, David V Serreze
MGI ID:	MGI:3785516
Synonyms:	DL309, RIPE3DL309
Transgene:	Tg(Ins2-E3*309)5Dvs  Location: unknown
Alliance:	Tg(Ins2-E3*309)5Dvs page

Strain of Origin:

NOD/ShiLtDvs

Transgene Type:    Transgenic (Inserted expressed sequence) Mutation:    Insertion   Mutation details: The rat insulin promoter was placed upstream of a mutant adenovirus early region (E3) sequences with a 750bp deletion that disrupts the 10.4K, 14.5K, and 14.7K genes, and a 6bp deletion in the 6.7K gene, leaving the gp19K and 11.6K genes expressed. (J:83195)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available

Original:	J:83195 Pierce MA, et al., Adenovirus early region 3 antiapoptotic 10.4K, 14.5K, and 14.7K genes decrease the incidence of autoimmune diabetes in NOD mice. Diabetes. 2003 May;52(5):1119-27
All:	1 reference(s)