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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Tg(Ins2-E3*309)5Dvs
transgene insertion 5, David V Serreze
MGI:3785516
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
tg1
 		Tg(Ins2-E3*309)5Dvs/? NOD/ShiLtDvs-Tg(Ins2-E3*309)5Dvs/Dvs MGI:3785517


Genotype
MGI:3785517
tg1
Allelic
Composition		 Tg(Ins2-E3*309)5Dvs/?
Genetic
Background		 NOD/ShiLtDvs-Tg(Ins2-E3*309)5Dvs/Dvs
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(Ins2-E3*309)5Dvs mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
decreased susceptibility to autoimmune diabetes ( J:83195 )
• 77% of females have diabetes at 30 weeks of age, while 95% of the non-transgenic NOD/ShiLtDvs have diabetes by 30 weeks of age




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory