Mki67 Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:130339 Minami S, et al., HB-EGF decelerates cell proliferation synergistically with TGFalpha in perinatal distal lung development. Dev Dyn. 2008 Jan;237(1):247-58
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:3785457
Gene symbol:	Mki67
Gene name:	antigen identified by monoclonal antibody Ki 67

Antibody:	anti-Ki67 (NCL-Ki67p)
Detection system:	Secondary antibody coupled to biotin

Results

5Aa ©

Specimen 5Aa: embryonic day 19.5 (more

)

Structure	Level	Pattern	Image	Note
TS26: lung	Present		5Aa

5Ab ©

Specimen 5Ab: embryonic day 19.5; Hbegf^tm1.1Mek/Hbegf^tm1.1Mek (more

)

Structure	Level	Pattern	Image	Note
TS26: lung	Strong		5Ab

5B E18.5 +/+ ©

Specimen 5B E18.5 +/+: embryonic day 18.5 (more

)
Note: The data are shown as a graph of percentages of Ki67-positive cells in total lung cells.

Structure	Level	Pattern	Image	Note
TS26: lung	Present		5B E18.5 +/+

5B E18.5 del/del ©

Specimen 5B E18.5 del/del: embryonic day 18.5; Hbegf^tm1.1Mek/Hbegf^tm1.1Mek (more

)
Note: The data are shown as a graph of percentages of Ki67-positive cells in total lung cells.

Structure	Level	Pattern	Image	Note
TS26: lung	Present		5B E18.5 del/del	There was an increase in expression compared to wild-type.

5B E19.5 +/+ ©

Specimen 5B E19.5 +/+: embryonic day 19.5 (more

)
Note: The data are shown as a graph of percentages of Ki67-positive cells in total lung cells.

Structure	Level	Pattern	Image	Note
TS26: lung	Present		5B E19.5 +/+

5B E19.5 del/del ©

Specimen 5B E19.5 del/del: embryonic day 19.5; Hbegf^tm1.1Mek/Hbegf^tm1.1Mek (more

)
Note: The data are shown as a graph of percentages of Ki67-positive cells in total lung cells.

Structure	Level	Pattern	Image	Note
TS26: lung	Present		5B E19.5 del/del	There was an increase in expression compared to wild-type.

5B P0 +/+ ©

Specimen 5B P0 +/+: postnatal day 0 (more

)
Note: The data are shown as a graph of percentages of Ki67-positive cells in total lung cells.

Structure	Level	Pattern	Image	Note
TS27: lung	Present		5B P0 +/+

5B P0 del/del ©

Specimen 5B P0 del/del: postnatal day 0; Hbegf^tm1.1Mek/Hbegf^tm1.1Mek (more

)
Note: The data are shown as a graph of percentages of Ki67-positive cells in total lung cells.

Structure	Level	Pattern	Image	Note
TS27: lung	Present		5B P0 del/del	There was an increase in expression compared to wild-type.

6Ca ©

Specimen 6Ca: postnatal day 0 (more

)

Structure	Level	Pattern	Image	Note
TS27: lung	Present		6Ca

6Cb ©

Specimen 6Cb: postnatal day 0; Tgfa^tm1Ard/Tgfa^tm1Ard (more

)

Structure	Level	Pattern	Image	Note
TS27: lung	Present		6Cb

6Cc ©

Specimen 6Cc: postnatal day 0; Hbegf^tm1.1Mek/Hbegf⁺, Tgfa^tm1Ard/Tgfa^tm1Ard (more

)

Structure	Level	Pattern	Image	Note
TS27: lung	Present		6Cc	The ratio of positive cells to the total cells was significantly increased in this mutant.

6Cd ©

Specimen 6Cd: postnatal day 0; Hbegf^tm1.1Mek/Hbegf^tm1.1Mek (more

)

Structure	Level	Pattern	Image	Note
TS27: lung	Present		6Cd

6Ce ©

Specimen 6Ce: postnatal day 0; Hbegf^tm1.1Mek/Hbegf^tm1.1Mek, Tgfa^tm1Ard/Tgfa⁺ (more

)

Structure	Level	Pattern	Image	Note
TS27: lung	Present		6Ce	The ratio of positive cells to the total cells was significantly increased in this mutant.

6D +/+ ©

Specimen 6D +/+: postnatal day 0 (more

)
Note: The data are shown as a graph of percentages of Ki67-positive cells in total lung cells.

Structure	Level	Pattern	Image	Note
TS27: lung	Present		6D +/+

6D +/+;+/- ©

Specimen 6D +/+;TGFa+/-: postnatal day 0; Tgfa^tm1Ard/Tgfa⁺ (more

)
Note: The data are shown as a graph of percentages of Ki67-positive cells in total lung cells.

Structure	Level	Pattern	Image	Note
TS27: lung	Present		6D +/+;+/-

6D +/-;-/- ©

Specimen 6D HB-EGFdel/+;TGFa-/-: postnatal day 0; Hbegf^tm1.1Mek/Hbegf⁺, Tgfa^tm1Ard/Tgfa^tm1Ard (more

)
Note: The data are shown as a graph of percentages of Ki67-positive cells in total lung cells.

Structure	Level	Pattern	Image	Note
TS27: lung	Present		6D +/-;-/-

6D -/-;+/+ ©

Specimen 6D HB-EGFdel/del;TGFa+/+: postnatal day 0; Hbegf^tm1.1Mek/Hbegf^tm1.1Mek (more

)
Note: The data are shown as a graph of percentages of Ki67-positive cells in total lung cells.

Structure	Level	Pattern	Image	Note
TS27: lung	Present		6D -/-;+/+

6D -/-;+/- ©

Specimen 6D HB-EGFdel/del;TGFa+/-: postnatal day 0; Hbegf^tm1.1Mek/Hbegf^tm1.1Mek, Tgfa^tm1Ard/Tgfa⁺ (more

)
Note: The data are shown as a graph of percentages of Ki67-positive cells in total lung cells.

Structure	Level	Pattern	Image	Note
TS27: lung	Present		6D -/-;+/-

7Ca ©

Specimen 7Ca +/+: postnatal day 0 (more

)

Structure	Level	Pattern	Image	Note
TS27: lung	Present		7Ca

7Cb ©

Specimen 7Cb: postnatal day 0; Egfr^wa2/Egfr^wa2 (more

)

Structure	Level	Pattern	Image	Note
TS27: lung	Present		7Cb

7Cc ©

Specimen 7Cc: postnatal day 0; Egfr^wa2/Egfr^wa2, Hbegf^tm1.1Mek/Hbegf⁺ (more

)

Structure	Level	Pattern	Image	Note
TS27: lung	Present		7Cc

7Cd ©

Specimen 7Cd: postnatal day 0; Hbegf^tm1.1Mek/Hbegf^tm1.1Mek (more

)

Structure	Level	Pattern	Image	Note
TS27: lung	Present		7Cd

7Ce ©

Specimen 7Ce: postnatal day 0; Egfr^wa2/Egfr⁺, Hbegf^tm1.1Mek/Hbegf^tm1.1Mek (more

)

Structure	Level	Pattern	Image	Note
TS27: lung	Present		7Ce

7Cf ©

Specimen 7Cf: postnatal day 0; Egfr^wa2/Egfr^wa2, Hbegf^tm1.1Mek/Hbegf^tm1.1Mek (more

)

Structure	Level	Pattern	Image	Note
TS27: lung	Present		7Cf

7D +/+ ©

Specimen 7D +/+: postnatal day 0 (more

)
Note: The data are shown as a graph of percentages of Ki67-positive cells in total lung cells.

Structure	Level	Pattern	Image	Note
TS27: lung	Present		7D +/+

Specimen 7D HB-EGF+/+;wa2/wa2: postnatal day 0; Egfr^wa2/Egfr^wa2 (more

)
Note: The data are shown as a graph of percentages of Ki67-positive cells in total lung cells.

Structure	Level	Pattern	Image	Note
TS27: lung	Present		7D +/+;wa2/wa2	The ratio of positive cells to the total cells was significantly increased.

Specimen 7D HB-EGFdel/+;wa2/wa2: postnatal day 0; Egfr^wa2/Egfr^wa2, Hbegf^tm1.1Mek/Hbegf⁺ (more

)
Note: The data are shown as a graph of percentages of Ki67-positive cells in total lung cells.

Structure	Level	Pattern	Image	Note
TS27: lung	Present		7D del/+;wa2/wa2

Specimen 7D HB-EGFdel/del;+/+: postnatal day 0; Hbegf^tm1.1Mek/Hbegf^tm1.1Mek (more

)
Note: The data are shown as a graph of percentages of Ki67-positive cells in total lung cells.

Structure	Level	Pattern	Image	Note
TS27: lung	Present		7D del/del;+/+	The ratio of positive cells to the total cells was significantly increased.

Specimen 7D del/del;wa2/+: postnatal day 0; Egfr^wa2/Egfr⁺, Hbegf^tm1.1Mek/Hbegf^tm1.1Mek (more

)
Note: The data are shown as a graph of percentages of Ki67-positive cells in total lung cells.

Structure	Level	Pattern	Image	Note
TS27: lung	Present		7D del/del;wa2/+

Specimen 7D del/del;wa2/wa2: postnatal day 0; Egfr^wa2/Egfr^wa2, Hbegf^tm1.1Mek/Hbegf^tm1.1Mek (more

)
Note: The data are shown as a graph of percentages of Ki67-positive cells in total lung cells.

Structure	Level	Pattern	Image	Note
TS27: lung	Present		7D del/del;wa2/wa2

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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