Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Gpamtm1.1Dali
Name:	glycerol-3-phosphate acyltransferase, mitochondrial; targeted mutation 1.1, Daniel Linden
MGI ID:	MGI:3785384
Gene:	Gpam  Location: Chr19:55056067-55115666 bp, - strand  Genetic Position: Chr19, 50.81 cM
Alliance:	Gpamtm1.1Dali page

Germline Transmission:	Earliest citation of germline transmission: J:134068
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted Mutation:    Intragenic deletion   Mutation details: Germ line, cre-mediated recombination was used to remove exons 3 and 4. The absence of protein product was confirmed by western blot analysis on liver mitochondria extracts, however, some activity is detected in microsomes. (J:130468)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

2 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gpam Mutation:	52 strains or lines available

Original:	J:134068 Yazdi M, et al., The role of mitochondrial glycerol-3-phosphate acyltransferase-1 in regulating lipid and glucose homeostasis in high-fat diet fed mice. Biochem Biophys Res Commun. 2008 May 16;369(4):1065-70
All:	2 reference(s)