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Hax1tm1Jni
Targeted Allele Detail
Summary
Symbol: Hax1tm1Jni
Name: HCLS1 associated X-1; targeted mutation 1, James N Ihle
MGI ID: MGI:3777018
Gene: Hax1  Location: Chr3:89902753-89906023 bp, - strand  Genetic Position: Chr3, 39.19 cM, cytoband F2
Alliance: Hax1tm1Jni page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:132627
Parent Cell Line:  E14 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe coding region was replaced with a neo cassette. The absence of protein product was confirmed by western blot analysis on thymocyte extracts. (J:132627)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Hax1 Mutation:  36 strains or lines available
References
Original:  J:132627 Chao JR, et al., Hax1-mediated processing of HtrA2 by Parl allows survival of lymphocytes and neurons. Nature. 2008 Mar 6;452(7183):98-102
All:  7 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/12/2024
MGI 6.23
The Jackson Laboratory