Eomestm1Rob
Targeted Allele Detail
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Symbol: |
Eomestm1Rob |
Name: |
eomesodermin; targeted mutation 1, Elizabeth J Robertson |
MGI ID: |
MGI:3774027 |
Synonyms: |
EomesCA, Tbr2/EomesCA |
Gene: |
Eomes Location: Chr9:118307259-118315176 bp, + strand Genetic Position: Chr9, 70.21 cM, cytoband F3
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Alliance: |
Eomestm1Rob page
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Eomestm1Rob/Eomestm2.1Rob Edil3Tg(Sox2-cre)1Amc/0 embryos fail to form the mesoderm cell layer and are blocked in gastrulation
Show the 1 phenotype image(s) involving this allele.
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Germline Transmission: |
Earliest citation of germline transmission:
J:131055
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Parent Cell Line: |
CCE/EK.CCE (ES Cell)
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Strain of Origin: |
129S/SvEv-Gpi1c
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Allele Type: |
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Targeted (Conditional ready, No functional change) |
Mutation: |
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Insertion
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Mutation details: A floxed neo cassette was inserted into intron 5-6 and additional loxP site was inserted into intron 1-2. This resulted in the floxing of exons 2 through 5. Transient Cre expression was used to removed the neo cassette.
(J:131055)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Eomes Mutation: |
41 strains or lines available
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Original: |
J:131055 Arnold SJ, et al., Pivotal roles for eomesodermin during axis formation, epithelium-to-mesenchyme transition and endoderm specification in the mouse. Development. 2008 Feb;135(3):501-11 |
All: |
16 reference(s) |
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