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Atrnl1tm1Gsb
Targeted Allele Detail
Summary
Symbol: Atrnl1tm1Gsb
Name: attractin like 1; targeted mutation 1, Gregory S Barsh
MGI ID: MGI:3773080
Synonyms: Atrnl1tar
Gene: Atrnl1  Location: Chr19:57599466-58121775 bp, + strand  Genetic Position: Chr19, 53.31 cM
Alliance: Atrnl1tm1Gsb page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:130463
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation details40 nucleotides in exon 24 were replaced with a lacZ-neo cassette, a strong splice acceptor and polyadenylation signal resulting in an alternate splicing event that excludes the transmemebrane domain encoding sequence. The authors state that this allele is likely to produce a functionally null protein. (J:130463)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Atrnl1 Mutation:  72 strains or lines available
References
Original:  J:130463 Walker WP, et al., Genetic analysis of attractin homologs. Genesis. 2007 Dec;45(12):744-56
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory