About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Atrnl1tm1Gsb
targeted mutation 1, Gregory S Barsh
MGI:3773080
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Atrnl1tm1Gsb/Atrnl1tm1Gsb involves: 129S1/Sv * 129X1/SvJ * C3H * C3HeB/FeJ MGI:3773147
cx2
Atrnmg-3J/Atrnmg-3J
Atrnl1tm1Gsb/Atrnl1tm1Gsb
involves: 129S1/Sv * 129X1/SvJ * C3H * C3HeB/FeJ MGI:3773151


Genotype
MGI:3773147
hm1
Allelic
Composition
Atrnl1tm1Gsb/Atrnl1tm1Gsb
Genetic
Background
involves: 129S1/Sv * 129X1/SvJ * C3H * C3HeB/FeJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Atrnl1tm1Gsb mutation (0 available); any Atrnl1 mutation (72 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
nervous system
N
• mice display normal brain morphology unlike mice with other alleles of Atrn1

integument
N
• unlike Atrnmg-3J homozygotes, mice display a wild-type coat color on an Agouti background




Genotype
MGI:3773151
cx2
Allelic
Composition
Atrnmg-3J/Atrnmg-3J
Atrnl1tm1Gsb/Atrnl1tm1Gsb
Genetic
Background
involves: 129S1/Sv * 129X1/SvJ * C3H * C3HeB/FeJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Atrnl1tm1Gsb mutation (0 available); any Atrnl1 mutation (72 available)
Atrnmg-3J mutation (2 available); any Atrn mutation (89 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
nervous system
• mice develop progressive vacuolation of the brain similar to Atrnmg-3J homozygotes

cardiovascular system
• by 6 months of age some mice develop cardiomyopathy

muscle
• by 6 months of age some mice develop cardiomyopathy





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
05/07/2024
MGI 6.23
The Jackson Laboratory