About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:128545 Visel A, et al., Comprehensive analysis of the expression patterns of the adenylate cyclase gene family in the developing and adult mouse brain. J Comp Neurol. 2006 Jun 10;496(5):684-97
Assay type: RNA in situ
MGI Accession ID: MGI:3768395
Gene symbol: Adcy2
Gene name: adenylate cyclase 2
Probe: MH957 probe 822
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Assay notes: A dual signal amplification strategy, termed catalyzed reporter deposition (CARD), was used for detection.
Results
Specimen Table 2-P7: postnatal day 7 (more )
Structure Level Pattern Image Note
TS28: main olfactory bulb glomerular layer Moderate MH1122
TS28: main olfactory bulb external plexiform layer Absent MH1122
TS28: main olfactory bulb mitral cell layer Strong MH1122
TS28: main olfactory bulb internal plexiform layer Absent MH1122
TS28: main olfactory bulb granule cell layer Strong MH1122
TS28: cerebral cortex Moderate MH1122
TS28: hippocampus CA1 Weak MH1122
TS28: hippocampus CA2 Weak MH1122
TS28: hippocampus CA3 Moderate MH1122
TS28: dentate gyrus Weak MH1122
TS28: corpus striatum Strong Single cells MH1122
TS28: telencephalon septum Weak MH1122
TS28: amygdala Weak MH1122
TS28: thalamus Strong MH1122
TS28: hypothalamus Moderate MH1122
TS28: pretectum Moderate MH1122
TS28: superior colliculus Weak MH1122
TS28: inferior colliculus Weak MH1122
TS28: midbrain tegmentum Weak MH1122
TS28: cerebellum molecular layer Absent MH1122
TS28: cerebellum Purkinje cell layer Absent MH1122
TS28: cerebellum granule cell layer Weak MH1122
TS28: pons Moderate MH1122
TS28: medulla oblongata Moderate MH1122
Specimen Table 2-P56: postnatal day 56 (more )
Structure Level Pattern Image Note
TS28: main olfactory bulb glomerular layer Moderate MH1904 , BA101
TS28: main olfactory bulb external plexiform layer Absent MH1904 , BA101
TS28: main olfactory bulb mitral cell layer Strong BA101 , MH1904
TS28: main olfactory bulb internal plexiform layer Absent BA101 , MH1904
TS28: main olfactory bulb granule cell layer Strong MH1904 , BA101
TS28: cerebral cortex Moderate MH1904 , BA101
TS28: hippocampus CA1 Strong BA101 , MH1904
TS28: hippocampus CA2 Absent BA101 , MH1904
TS28: hippocampus CA3 Weak BA101 , MH1904
TS28: dentate gyrus Moderate MH1904 , BA101
TS28: corpus striatum Strong Single cells MH1904 , BA101
TS28: telencephalon septum Weak MH1904 , BA101
TS28: amygdala Weak MH1904 , BA101
TS28: thalamus Strong MH1904 , BA101
TS28: hypothalamus Moderate BA101 , MH1904
TS28: pretectum Moderate BA101 , MH1904
TS28: superior colliculus Weak MH1904 , BA101
TS28: inferior colliculus Weak BA101 , MH1904
TS28: midbrain tegmentum Weak BA101 , MH1904
TS28: cerebellum molecular layer Absent BA101 , MH1904
TS28: cerebellum Purkinje cell layer Absent BA101 , MH1904
TS28: cerebellum granule cell layer Weak BA101 , MH1904
TS28: pons Moderate BA101 , MH1904
TS28: medulla oblongata Moderate BA101 , MH1904
Specimen 1A: postnatal day 56 (more )
Note: This is a sagittal section.
Structure Level Pattern Image Note
TS28: main olfactory bulb glomerular layer Strong 1A
TS28: main olfactory bulb mitral cell layer Strong 1A
TS28: main olfactory bulb granule cell layer Present 1A
Specimen Not shown: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: cerebral cortex Absent
TS22: main olfactory bulb Absent
TS22: thalamus Absent
TS22: diencephalon Strong Regionally restricted Expression is present in the mammillary body.
Specimen 2B: postnatal day 56 (more )
Note: This is a coronal section.
Structure Level Pattern Image Note
TS28: cortical layer II Present 2B Expression is present in layers 2/3. This is one of layers with the highest expression levels.
TS28: cortical layer III Present 2B Expression is present in layers 2/3. This is one of layers with the highest expression levels.
TS28: cortical layer V Present 2B This is one of layers with the highest expression levels.
Specimen 3C: postnatal day 7 (more )
Note: This is a sagittal section.
Structure Level Pattern Image Note
TS28: hippocampus CA3 Weak 3C There is low or no expression.
TS28: dentate gyrus hilus Strong 3C
Specimen 3D: postnatal day 56 (more )
Note: This is a coronal section.
Structure Level Pattern Image Note
TS28: hippocampus CA1 Strong 3D
TS28: dentate gyrus Moderate 3D
TS28: hippocampus CA3 Weak 3D
Specimen 4B: postnatal day 7 (more )
Note: This is a sagittal section.
Structure Level Pattern Image Note
TS28: corpus striatum Present Single cells 4B Expression is restricted to a small subset of striatal cells.
Specimen 4E: postnatal day 56 (more )
Note: This is a coronal section in the anterior striatum.
Structure Level Pattern Image Note
TS28: corpus striatum Present Single cells 4H , 4E Expression is restricted to a small subset of striatal cells.
Specimen 4K: postnatal day 56 (more )
Note: This is a coronal section from a more posterior region of the striatum.
Structure Level Pattern Image Note
TS28: corpus striatum Present Single cells 4K Expression is restricted to a small subset of striatal cells.
Specimen 5G: postnatal day 7 (more )
Structure Level Pattern Image Note
TS28: reticular thalamic nucleus Strong 5G
TS28: zona incerta Strong 5G
TS28: pretectum Present 5G
Specimen 5H: postnatal day 56 (more )
Structure Level Pattern Image Note
TS28: reticular thalamic nucleus Strong 5H
TS28: zona incerta Strong 5H
TS28: pretectum Present 5H
Specimen 5I: postnatal day 7 (more )
Structure Level Pattern Image Note
TS28: anterior thalamic group Strong 5I There is strong expression in the anterodorsal thalamic nucleus.
Specimen 5J: postnatal day 56 (more )
Structure Level Pattern Image Note
TS28: anterior thalamic group Strong 5J There is strong expression in the anterodorsal thalamic nucleus.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
05/07/2024
MGI 6.23 		The Jackson Laboratory