Summary | Transgene origin | Transgene description | Phenotypes | Disease models | Find Mice (IMSR) | References

Symbol:	Tg(Thy1-EGFP)MJrs
Name:	transgene insertion M, Joshua R Sanes
MGI ID:	MGI:3766828
Synonyms:	GFP line-M, GFP-M, Thy1-GFP line M, Thy1-GFPM, Thy1-GFP/M, Thy1::GFP-M
Transgene:	Tg(Thy1-EGFP)MJrs  Location: unknown
Alliance:	Tg(Thy1-EGFP)MJrs page

Strain of Origin:

(C57BL/6J x CBA)F1

Transgene Type:    Transgenic (Reporter) Mutation:    Insertion   Mutation details: The Thy1-GFP transgene was designed with a modified regulatory region of the "murine thy1.2 gene" (extending from the promoter to the intron following exon 4, excluding exon 3 and its flanking introns) upstream of an enhanced green fluorescent protein (EGFP) sequence. Line M was subsequently established and analyzed. Expression of EGFP is detected primarily in mossy fibers in internal granule layer of the cerebellum (10-80% incidence). Less than 10% of all motor axons, retinal ganglion cells, lumbar dorsal root ganglion, and cortex express EGFP, with no reported expression in other tested neuronal tissues. (J:93699)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available

Original:	J:93699 Feng G, et al., Imaging neuronal subsets in transgenic mice expressing multiple spectral variants of GFP. Neuron. 2000 Oct;28(1):41-51
All:	185 reference(s)