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Map3k12Gt(RRN366)Byg
Gene trapped Allele Detail
Summary
Symbol: Map3k12Gt(RRN366)Byg
Name: mitogen-activated protein kinase kinase kinase 12; gene trap RRN366, BayGenomics
MGI ID: MGI:3760641
Synonyms: DLK, zpktp
Gene: Map3k12  Location: Chr15:102406079-102425311 bp, - strand  Genetic Position: Chr15, 57.63 cM, cytoband F3
Alliance: Map3k12Gt(RRN366)Byg page
Mutation
origin
Mutant Cell Line:  RRN366
Germline Transmission:  Earliest citation of germline transmission: J:125702
Parent Cell Line:  Other (see notes) (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Gene trapped (Null/knockout, Reporter)
Mutation:    Insertion of gene trap vector     Vector: pGT0Lxf     Vector Type: gene trap
 
Mutation details: The gene trap vector pGT0Lxf was inserted into an intron in the 5' untranslated region. This allele is strongly hypomorphic. (J:125702)
Sequence Tags: 
Sequence tag details (1 tag)
Genome Context: 
Genome Browser view of this mutation
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Map3k12 Mutation:  39 strains or lines available
Notes
All BayGenomics gene trap mutations were generated in either CGR8 or E14TG2a (129P2/OlaHsd) parental ES cell lines, with the majority in subline E14TG2a.4. The specific ES cell line in which each mutation was made is not specified.
References
Original:  J:125702 Bloom AJ, et al., The requirement for Phr1 in CNS axon tract formation reveals the corticostriatal boundary as a choice point for cortical axons. Genes Dev. 2007 Oct 15;21(20):2593-606
All:  7 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory