Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Pgm3mld1
Name:	phosphoglucomutase 3; multilineage defect 1
MGI ID:	MGI:3758645
Gene:	Pgm3  Location: Chr9:86436430-86453895 bp, - strand  Genetic Position: Chr9, 46.58 cM, cytoband E3.2
Alliance:	Pgm3mld1 page

Strain of Origin:

C57BL/6

Allele Type:    Chemically induced (ENU) Mutation:    Single point mutation   Mutation details: A T to A transversion was induced by ENU mutagenisis in the fourth intron 14 bp upstream of exon 5. A complimentation assay was performed to determine the gene affected. While a transcript is detectable by RT-PCR the resulting protein has less than 1% of wild-type enzymatic activity in the testes, spleen, pancreas and heart. (J:125094) Inheritance:    Recessive

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

7 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Pgm3 Mutation:	39 strains or lines available

Original:	J:125094 Greig KT, et al., Agm1/Pgm3-mediated sugar nucleotide synthesis is essential for hematopoiesis and development. Mol Cell Biol. 2007 Aug;27(16):5849-59
All:	1 reference(s)