Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Mstntm1Swel
Name:	myostatin; targeted mutation 1, Stephen Welle
MGI ID:	MGI:3711219
Synonyms:	Mstnf, Mstn[f]
Gene:	Mstn  Location: Chr1:53100799-53107238 bp, + strand  Genetic Position: Chr1, 26.99 cM
Alliance:	Mstntm1Swel page

Germline Transmission:	Earliest citation of germline transmission: J:106054
Parent Cell Line:	AB1 (ES Cell)
Strain of Origin:	129S7/SvEvBrd-Hprt1+

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion     LoxP sites were inserted to flank exon 3, which encodes the entire active portion of the peptide. (J:106054)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Mstn Mutation:	33 strains or lines available

Original:	J:106054 Welle S, et al., Myofibrillar protein synthesis in myostatin-deficient mice. Am J Physiol Endocrinol Metab. 2006 Mar;290(3):E409-15
All:	11 reference(s)