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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Mstntm1Swel
targeted mutation 1, Stephen Welle
MGI:3711219
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Mstntm1Swel/Mstntm1Swel
Tg(CAG-cre/Esr1*)5Amc/? 		involves: 129S7/SvEvBrd-Hprt1 * C57BL/6 * CBA MGI:3711528


Genotype
MGI:3711528
cn1
Allelic
Composition		 Mstntm1Swel/Mstntm1Swel
Tg(CAG-cre/Esr1*)5Amc/?
Genetic
Background		 involves: 129S7/SvEvBrd-Hprt1 * C57BL/6 * CBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mstntm1Swel mutation (1 available); any Mstn mutation (33 available)
Tg(CAG-cre/Esr1*)5Amc mutation (9 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
muscle
increased skeletal muscle fiber diameter ( J:121233 )
• the mean cross-sectional area of an individual quadriceps fibers in tamoxifen treated mice is 42% greater than in treated controls
increased skeletal muscle mass ( J:121233 )
• after 3 months of tamoxifen treatment muscle mass is increased by 25% compared to untreated mice and treated wild-type mice in the gastrocnemius and quadriceps of males and females




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
05/21/2024
MGI 6.23 		The Jackson Laboratory