About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:118222 Vauti F, et al., The mouse Trm1-like gene is expressed in neural tissues and plays a role in motor coordination and exploratory behaviour. Gene. 2007 Mar 15;389(2):174-85
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:3707512
Gene symbol: Trmt1l
Gene name: tRNA methyltransferase 1 like
Reporter: lacZ
Direct Detection
Assay notes: Specimens were fixed in 2% paraformaldehyde and 0.25% glutaraldehyde.
Results
Specimen 4A: embryonic day 10.5; Trmt1lGt(W027A02)Wrst/Trmt1l+ (more )
Structure Level Pattern Image Note
TS18: heart Present 4A

Specimen 4B: embryonic day 11.5; Trmt1lGt(W027A02)Wrst/Trmt1l+ (more )
Structure Level Pattern Image Note
TS19: heart Present 4B

Specimen 4C: embryonic day 12.5; Trmt1lGt(W027A02)Wrst/Trmt1l+ (more )
Structure Level Pattern Image Note
TS20: choroid plexus Strong 4C
TS20: spinal ganglion Strong 4C
TS20: trigeminal ganglion Strong 4C

Specimen 4D: embryonic day 12.5; Trmt1lGt(W027A02)Wrst/Trmt1l+ (more )
Structure Level Pattern Image Note
TS20: trigeminal ganglion Strong 4D
TS20: trigeminal nerve Strong 4D

Specimen 4E: embryonic day 13.5; Trmt1lGt(W027A02)Wrst/Trmt1l+ (more )
Structure Level Pattern Image Note
TS21: choroid plexus Strong 4E
TS21: spinal ganglion Strong 4E

Specimen 4F: embryonic day 14.5; Trmt1lGt(W027A02)Wrst/Trmt1l+ (more )
Structure Level Pattern Image Note
TS22: heart Strong 4F
TS22: spinal ganglion Strong 4F
TS22: trigeminal ganglion Strong 4F
TS22: facial ganglion Present 4F Expression in the nucleus facialis.

Specimen 4G: embryonic day 15.5; Trmt1lGt(W027A02)Wrst/Trmt1l+ (more )
Structure Level Pattern Image Note
TS23: olfactory epithelium Present 4G
TS23: choroid plexus Strong 4G
TS23: heart Strong 4G
TS23: spinal ganglion Strong 4G
TS23: trigeminal ganglion Strong 4G

Specimen 4H: embryonic day 16.5; Trmt1lGt(W027A02)Wrst/Trmt1l+ (more )
Structure Level Pattern Image Note
TS24: choroid plexus Present 4H
TS24: heart Present 4H
TS24: olfactory epithelium Present 4H
TS24: brown fat Present 4H

Specimen 4I: embryonic day 16.5; Trmt1lGt(W027A02)Wrst/Trmt1l+ (more )
Structure Level Pattern Image Note
TS24: choroid plexus Present 4I
TS24: olfactory epithelium Present 4I
TS24: nasopharynx Present 4I Expression in the nasopharyngeal tract.
TS24: epiglottis Present 4I
TS24: esophagus Present 4I
TS24: medulla oblongata Present 4I
TS24: midbrain Present 4I
TS24: thalamus Present 4I
TS24: brain ventricular layer Present 4I Expression in the ependyma.
TS24: spinal cord meninges Present 4I

Specimen 4J: embryonic day 16.5; Trmt1lGt(W027A02)Wrst/Trmt1l+ (more )
Structure Level Pattern Image Note
TS24: heart Present 4J
TS24: lung Present 4J
TS24: axial skeleton Present 4J Expression in the vertebral column.
TS24: intervertebral disc Present 4J
TS24: spinal cord Present 4J

Specimen 4K: embryonic day 18.5; Trmt1lGt(W027A02)Wrst/Trmt1l+ (more )
Note: Specimens were embedded in gelatine/albumin prior to sectioning.
Structure Level Pattern Image Note
TS26: bronchus epithelium Present 4K Expression in the bronchial epithelium.

Specimen 5A E18.5: embryonic day 18.5; Trmt1lGt(W027A02)Wrst/Trmt1l+ (more )
Note: Specimens were embedded in gelatine/albumin prior to sectioning.
Structure Level Pattern Image Note
TS26: main olfactory bulb Present 5A E18.5
TS26: cerebral cortex Present 5A E18.5 Expression in the neocortex.
TS26: medulla oblongata Present 5A E18.5
TS26: midbrain Present 5A E18.5
TS26: thalamus Present 5A E18.5
TS26: cerebellum Present Regionally restricted 5A E18.5 No expression in the cerebellum white matter.

Specimen 5A P4: postnatal day 4; Trmt1lGt(W027A02)Wrst/Trmt1l+ (more )
Note: Specimens were embedded in gelatine/albumin prior to sectioning.
Structure Level Pattern Image Note
TS28: main olfactory bulb Present 5A P4
TS28: cerebral cortex Present 5A P4 Expression in the neocortex.
TS28: thalamus Present 5A P4
TS28: abducens nucleus Present 5A P4
TS28: dorsal motor nucleus of vagus nerve Present 5A P4
TS28: facial nucleus Present 5A P4
TS28: hypoglossal nucleus Present 5A P4
TS28: oculomotor nucleus Present 5A P4
TS28: red nucleus Present 5A P4
TS28: trigeminal nucleus Present 5A P4
TS28: brain ependyma Present 5A P4
TS28: cerebral aqueduct Present 5A P4
TS28: choroid plexus Present 5A P4
TS28: cerebellum Present Regionally restricted 5A P4
TS28: cerebellum white matter Absent 5A P4

Specimen 5A P20: postnatal day 20; Trmt1lGt(W027A02)Wrst/Trmt1l+ (more )
Note: Specimens were embedded in gelatine/albumin prior to sectioning.
Structure Level Pattern Image Note
TS28: main olfactory bulb Present 5A P20
TS28: cerebral cortex Present 5A P20 Expression in the neocortex.
TS28: corpus striatum Present 5A P20
TS28: medulla oblongata Present 5A P20
TS28: midbrain Present 5A P20
TS28: thalamus Present 5A P20
TS28: cerebellum Present Regionally restricted 5A P20
TS28: cerebellum white matter Absent 5A P20

Specimen 5A adult: postnatal adult; Trmt1lGt(W027A02)Wrst/Trmt1l+ (more )
Note: Specimens were embedded in gelatine/albumin prior to sectioning.
Structure Level Pattern Image Note
TS28: main olfactory bulb Present 5A adult
TS28: cerebral cortex Present 5A adult Expression in the neocortex.
TS28: corpus striatum Present 5A adult
TS28: medulla oblongata Present 5A adult
TS28: midbrain Present 5A adult
TS28: thalamus Present 5A adult
TS28: cerebellum Present Regionally restricted 5A adult
TS28: cerebellum white matter Absent 5A adult

Specimen 5B E18.5: embryonic day 18.5; Trmt1lGt(W027A02)Wrst/Trmt1l+ (more )
Structure Level Pattern Image Note
TS26: brain Present Regionally restricted 5B E18.5

Specimen 5B adult: postnatal adult; Trmt1lGt(W027A02)Wrst/Trmt1l+ (more )
Structure Level Pattern Image Note
TS28: brain Strong Regionally restricted 5B adult

Specimen 5C adult: postnatal adult; Trmt1lGt(W027A02)Wrst/Trmt1l+ (more )
Note: Specimens were embedded in gelatine/albumin prior to sectioning.
Structure Level Pattern Image Note
TS28: cerebral internal capsule Present 5C adult
TS28: corpus callosum Present 5C adult
TS28: fornix Present 5C adult
TS28: cerebral hemisphere white matter Present Regionally restricted 5C adult Expression in the external capsule and stria terminalis.
TS28: cerebellum Present Regionally restricted 5C adult
TS28: hippocampus Present Regionally restricted 5C adult Expression in the hippocampal fissure.
TS28: cerebellum white matter Absent 5C adult

Specimen 6A: postnatal day 4; Trmt1lGt(W027A02)Wrst/Trmt1l+ (more )
Note: Specimens were embedded in gelatine/albumin prior to sectioning.
Structure Level Pattern Image Note
TS28: main olfactory bulb external plexiform layer Present 6A
TS28: main olfactory bulb glomerular layer Present 6A
TS28: main olfactory bulb mitral cell layer Present 6A

Specimen 6B: postnatal adult; Trmt1lGt(W027A02)Wrst/Trmt1l+ (more )
Note: Specimens were embedded in gelatine/albumin prior to sectioning.
Structure Level Pattern Image Note
TS28: main olfactory bulb external plexiform layer Present 6B
TS28: main olfactory bulb glomerular layer Present 6B
TS28: main olfactory bulb mitral cell layer Strong 6B
TS28: main olfactory bulb granule cell layer Weak 6B
TS28: main olfactory bulb internal plexiform layer Weak 6B

Specimen 6C: postnatal day 13; Trmt1lGt(W027A02)Wrst/Trmt1l+ (more )
Note: Specimens were embedded in gelatine/albumin prior to sectioning.
Structure Level Pattern Image Note
TS28: cortical layer IV Present 6C
TS28: cortical layer V Present 6C

Specimen 6D: postnatal adult; Trmt1lGt(W027A02)Wrst/Trmt1l+ (more )
Note: Specimens were embedded in gelatine/albumin prior to sectioning.
Structure Level Pattern Image Note
TS28: neocortex layer Present 6D Expression in all neocortical layers.

Specimen 6E: postnatal day 5; Trmt1lGt(W027A02)Wrst/Trmt1l+ (more )
Note: Specimens were embedded in gelatine/albumin prior to sectioning.
Structure Level Pattern Image Note
TS28: cerebral cortex Present 6E Expression in the neocortex.
TS28: thalamus Present 6E
TS28: corpus striatum Weak 6E

Specimen 6F: postnatal adult; Trmt1lGt(W027A02)Wrst/Trmt1l+ (more )
Note: Specimens were embedded in gelatine/albumin prior to sectioning.
Structure Level Pattern Image Note
TS28: cerebral cortex Strong 6F Expression in the neocortex.
TS28: corpus striatum Strong 6F

Specimen 6G: postnatal day 20; Trmt1lGt(W027A02)Wrst/Trmt1l+ (more )
Note: Specimens were embedded in gelatine/albumin prior to sectioning.
Structure Level Pattern Image Note
TS28: cerebellum Purkinje cell layer Present 6G
TS28: cerebellum granule cell layer Present 6G
TS28: cerebellum molecular layer Present 6G
TS28: cerebellum white matter Absent 6G

Specimen 6H: postnatal adult; Trmt1lGt(W027A02)Wrst/Trmt1l+ (more )
Note: Specimens were embedded in gelatine/albumin prior to sectioning.
Structure Level Pattern Image Note
TS28: cerebellum granule cell layer Present 6H
TS28: cerebellum white matter Absent 6H

Specimen 6I: postnatal day 2; Trmt1lGt(W027A02)Wrst/Trmt1l+ (more )
Note: Specimens were embedded in gelatine/albumin prior to sectioning.
Structure Level Pattern Image Note
TS27: brain ependyma Present 6I
TS27: hippocampus pyramidal cell layer Present 6I

Specimen 6J: postnatal day 13; Trmt1lGt(W027A02)Wrst/Trmt1l+ (more )
Note: Specimens were embedded in gelatine/albumin prior to sectioning.
Structure Level Pattern Image Note
TS28: hippocampus pyramidal cell layer Present 6J
TS28: hippocampus molecular layer Present 6J Expression in the lacunosum moleculare.

Specimen 6K: postnatal day 20; Trmt1lGt(W027A02)Wrst/Trmt1l+ (more )
Note: Specimens were embedded in gelatine/albumin prior to sectioning.
Structure Level Pattern Image Note
TS28: dentate gyrus polymorphic layer Present 6K
TS28: hippocampus pyramidal cell layer Present 6K
TS28: dentate gyrus molecular layer Present Regionally restricted 6K Expression in parts of the molecular layer.

Specimen 6L: postnatal adult; Trmt1lGt(W027A02)Wrst/Trmt1l+ (more )
Note: Specimens were embedded in gelatine/albumin prior to sectioning.
Structure Level Pattern Image Note
TS28: hippocampus pyramidal cell layer Present 6L
TS28: hippocampus molecular layer Present 6L Expression in the lacunosum moleculare.
TS28: dentate gyrus polymorphic layer Present 6L
TS28: hippocampus stratum radiatum Present 6L
TS28: dentate gyrus molecular layer Present Regionally restricted 6L Expression in parts of the molecular layer.
TS28: hippocampus stratum lucidum Present Single cells 6L
TS28: hippocampus stratum oriens Present Single cells 6L
TS28: hippocampus Present Regionally restricted 6L
TS28: dentate gyrus granule cell layer Absent 6L


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
04/30/2024
MGI 6.23
The Jackson Laboratory