Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Nedd9tm1Miku
Name:	neural precursor cell expressed, developmentally down-regulated gene 9; targeted mutation 1, Mineo Kurokawa
MGI ID:	MGI:3700233
Synonyms:	Cas-L-
Gene:	Nedd9  Location: Chr13:41463392-41640836 bp, - strand  Genetic Position: Chr13, 20.43 cM
Alliance:	Nedd9tm1Miku page

Germline Transmission:	Earliest citation of germline transmission: J:116716
Parent Cell Line:	TT2 (ES Cell)
Strain of Origin:	(C57BL/6NCrlj x CBA/JNCrlj)F1

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A 1.2 kb region that includes exon 2 was replaced with EGFP and a floxed neo cassette. Western blot analysis of homozygous thymus cell lysates confirmed absence of the full length protein. (J:116716)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

2 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Nedd9 Mutation:	34 strains or lines available

Original:	J:116716 Seo S, et al., Crk-associated substrate lymphocyte type is required for lymphocyte trafficking and marginal zone B cell maintenance. J Immunol. 2005 Sep 15;175(6):3492-501
All:	15 reference(s)