Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol: Lmtk2tm1Tya Name: lemur tyrosine kinase 2; targeted mutation 1, Tadashi Yamamoto MGI ID: MGI:3699255 Synonyms: Brek- Gene: Lmtk2  Location: Chr5:144037254-144125022 bp, + strand  Genetic Position: Chr5, 82.85 cM Alliance: Lmtk2tm1Tya page

Azoospermia in Lmtk2tm1Tya/Lmtk2tm1Tya mice Show the 3 phenotype image(s) involving this allele.

Germline Transmission:	Earliest citation of germline transmission: J:118247
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion     Exons 4-6 were replaced with a neomycin resistance gene. (J:118247)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

2 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Lmtk2 Mutation:	65 strains or lines available

Original:	J:118247 Kawa S, et al., Azoospermia in mice with targeted disruption of the Brek/Lmtk2 (brain-enriched kinase/lemur tyrosine kinase 2) gene. Proc Natl Acad Sci U S A. 2006 Dec 19;103(51):19344-9
All:	1 reference(s)