Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Hadhbm1Ytc
Name:	hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta; mutation 1, Yuan-Tsong Chen
MGI ID:	MGI:3698125
Synonyms:	Hadhbm1Yuan
Gene:	Hadhb  Location: Chr5:30360251-30389591 bp, + strand  Genetic Position: Chr5, 16.04 cM
Alliance:	Hadhbm1Ytc page

Strain of Origin:

C57BL/6J

Allele Type:    Chemically induced (ENU) Mutation:    Single point mutation   Mutation details: This allele contains a missense mutation of methionine to lysine at amino acid 404, resulting from a T-to-A transversion in exon 14. (J:117738)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

6 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Hadhb Mutation:	30 strains or lines available

Original:	J:117738 Kao HJ, et al., ENU mutagenesis identifies mice with cardiac fibrosis and hepatic steatosis caused by a mutation in the mitochondrial trifunctional protein beta-subunit. Hum Mol Genet. 2006 Dec 15;15(24):3569-77
All:	1 reference(s)