Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Hmga1tm2Afus
Name:	high mobility group AT-hook 1; targeted mutation 2, Alfredo Fusco
MGI ID:	MGI:3697313
Synonyms:	Hmga1-
Gene:	Hmga1  Location: Chr17:27775471-27782648 bp, + strand  Genetic Position: Chr17, 14.5 cM
Alliance:	Hmga1tm2Afus page

Germline Transmission:	Earliest citation of germline transmission: J:117669
Parent Cell Line:	AB2.1 (ES Cell)
Strain of Origin:	129S7/SvEvBrd-Hprt1b-m2

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: Exons V and VI were replaced with a neomycin resistance cassette. Northern blot analysis confirmed absence of transcripts in mutant ES cells. (J:117669)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Hmga1 Mutation:	21 strains or lines available

Original:	J:117669 Battista S, et al., Loss of Hmga1 gene function affects embryonic stem cell lympho-hematopoietic differentiation. FASEB J. 2003 Aug;17(11):1496-8
All:	2 reference(s)