Summary | Transgene origin | Transgene description | Expression | Recombinase activity | Phenotypes | Find Mice (IMSR) | References

Symbol:	Tg(Sim1-cre)1Lowl
Name:	transgene insertion 1, Bradford B Lowell
MGI ID:	MGI:3692526
Synonyms:	Sim1Cre, Sim1-Cre
Transgene:	Tg(Sim1-cre)1Lowl  Location: unknown
Alliance:	Tg(Sim1-cre)1Lowl page

Strain of Origin:

FVB

Transgene Type:    Transgenic (Recombinase) Mutation:    Insertion   Tg(Sim1-cre)1Lowl expression driven by 1 gene Transgene expression driven by: Organism Driver Gene Note Not Specified Sim1   Mutation details: The cre ATG was inserted via recombineering techniques, into the Sim1 ATG site of a BAC containing 137.1 kb of genomic C57BL/6 Sim1 sequences up to and including exon 8. The inserted cre sequence deleted the first 31 bp of the Sim1 gene. (J:115192)

Activity:	Tissue activity of this recombinase allele
Driver:	Sim1 (species not specified) Summary of all recombinase alleles driven by Sim1. Comparative matrix view of recombinase activities

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:

35 assay results

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 2 strains available      Cell Lines: 0 lines available

Original:	J:115192 Balthasar N, et al., Divergence of melanocortin pathways in the control of food intake and energy expenditure. Cell. 2005 Nov 4;123(3):493-505
All:	53 reference(s)