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Igktm2Rsky
Targeted Allele Detail
Summary
Symbol: Igktm2Rsky
Name: immunoglobulin kappa chain complex; targeted mutation 2, Klaus Rajewsky
MGI ID: MGI:3688312
Synonyms: 3-83kappaiJkappa-, Igktm2Pld
Gene: Igk  Location: Chr6:67532620-70703738 bp, + strand  Genetic Position: Chr6, 30.89 cM, cytoband F1-pter
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:111431
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Inserted expressed sequence)
Mutations:    Insertion, Intergenic deletion
 
Mutation detailsA targeting vector was used to insert a recombined Vk3-83-Jk5 region where all endogenous Jkappa segments are deleted. (J:111431)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Igk Mutation:  25 strains or lines available
References
Original:  J:111431 Pelanda R, et al., Receptor editing in a transgenic mouse model: site, efficiency, and role in B cell tolerance and antibody diversification. Immunity. 1997 Dec;7(6):765-75
All:  13 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/12/2024
MGI 6.23
The Jackson Laboratory