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Gene Expression Data
Assay Details
Assay
Reference: J:21528 Stayton CL, et al., Cloning and characterization of a new human Xq13 gene, encoding a putative helicase. Hum Mol Genet. 1994 Nov;3(11):1957-64
Assay type: RNA in situ
MGI Accession ID: MGI:3687976
Gene symbol: Atrx
Gene name: ATRX, chromatin remodeler
Probe: Mxnp cDNA1
Probe preparation: Antisense RNA
Visualized with: Autoradiography
Results
Specimen 4a: embryonic day 7.0 (more )
Note: The embryo is early primitive streak stage.
Structure Level Pattern Image Note
TS10: embryo Weak Non-Uniform 4a Expression was detected as a diffuse low-level signal.
TS10: amniotic fold Strong Regionally restricted 4a Expression was strong at the posterior amniotic fold.

Specimen 4b: embryonic day 7.0 (more )
Note: The embryo is early primitive streak stage.
Structure Level Pattern Image Note
TS10: embryo Weak Non-Uniform 4b Expression was detected as a diffuse low-level signal.
TS10: amniotic fold Strong Regionally restricted 4b Expression was strong at the posterior amniotic fold.

Specimen 4c: embryonic day 8.0 (more )
Structure Level Pattern Image Note
TS12: chorion Strong 4c
TS12: allantois Absent 4c Author stated that no other extra-embryonic tissues displayed signal at this stage.
TS12: amnion Absent 4c Author stated that no other extra-embryonic tissues displayed signal at this stage.
TS12: extraembryonic ectoderm Absent 4c Author stated that no other extra-embryonic tissues displayed signal at this stage.
TS12: extraembryonic endoderm Absent 4c Author stated that no other extra-embryonic tissues displayed signal at this stage.
TS12: extraembryonic mesenchyme Absent 4c Author stated that no other extra-embryonic tissues displayed signal at this stage.
TS12: trophectoderm Absent 4c Author stated that no other extra-embryonic tissues displayed signal at this stage.
TS12: yolk sac Absent 4c Author stated that no other extra-embryonic tissues displayed signal at this stage.
TS12: embryo Present 4c Embryonic expression was widespread.

Specimen 4d: embryonic day 11.5-12.0 (more )
Structure Level Pattern Image Note
TS19: Rathke's pouch Present 4d
TS19: diencephalon Present 4d
TS19: future spinal cord Present 4d
TS19: metencephalon Present 4d
TS19: midbrain Present 4d
TS19: myelencephalon Present 4d
TS19: telencephalon Present 4d
TS19: trunk Weak 4d Less expression was detected at the heart level.

Specimen 4e: embryonic day 13.0 (more )
Structure Level Pattern Image Note
TS21: trunk Weak 4e Expression in the trunk decreased at this stage.
TS21: diencephalon Absent 4e
TS21: medulla oblongata Absent 4e
TS21: spinal cord Absent 4e
TS21: choroid plexus Present Regionally restricted 4e Expression was detected in the choroid plexuses of the lateral ventricles and of the IV ventricle.
TS21: hypothalamus Present 4e
TS21: midbrain Present 4e
TS21: telencephalon Present Regionally restricted 4e Expression was detected in dorsal and basal telencephalon and a strong signal was observed in the periventricular layer of the hippocampus.
TS21: spinal ganglion Present 4e
TS21: trigeminal ganglion Present 4e

Specimen 4f: embryonic day 16.0-17.0 (more )
Structure Level Pattern Image Note
TS25: cortical plate Strong 4f
TS25: olfactory epithelium Strong 4f
TS25: telencephalon Present Regionally restricted 4f Expression was strong in the periventricular layer and in the cortical plate and was faint in the prefrontal area of the dorsal telencephalon but was absent in the fimbria.
TS25: olfactory lobe Strong Regionally restricted 4f Expression was strong in the neuroepithelium of the olfactory bulb.
TS25: choroid plexus Strong Regionally restricted 4f Expression was strong in the choroid plexus of the fourth ventricle.
TS25: remnant of Rathke's pouch Present 4f
TS25: cerebellum Present Regionally restricted 4f Expression was detected in the extra-ganglionic layer.

Specimen 4g: postnatal newborn (more )
Structure Level Pattern Image Note
TS27: hippocampus Strong 4g
TS27: main olfactory bulb Strong 4g
TS27: cerebral cortex Weak Uniform 4g
TS27: thalamus Absent 4g
TS27: cerebellum Strong Regionally restricted 4g Expression was strong throughout the marginal zone in the ganglionic and extraganglionic areas of the cerebellum.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory