Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Clic5jbg
Name:	chloride intracellular channel 5; jitterbug
MGI ID:	MGI:3663254
Gene:	Clic5  Location: Chr17:44445671-44591059 bp, + strand  Genetic Position: Chr17, 20.53 cM, cytoband C
Alliance:	Clic5jbg page

Strain of Origin:

C3H/HeJ

Allele Type:    Spontaneous (Null/knockout) Mutation:    Intragenic deletion   Mutation details: A 97 base pair deletion, including the 3'-most 87 base pairs of exon 5 and 10 base pairs of the flanking intron sequence including the exon/intron splice donor recognition sequence, results in a frame shift and premature stop codon in both Clic5A and Clic5B transcripts, effectively resulting in a null mutation of both transcripts. (J:112741) Inheritance:    Recessive

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	15 assay results
In Structures Affected by this Mutation:	9 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Clic5 Mutation:	20 strains or lines available

Original:	J:112741 Gagnon LH, et al., The chloride intracellular channel protein CLIC5 is expressed at high levels in hair cell stereocilia and is essential for normal inner ear function. J Neurosci. 2006 Oct 4;26(40):10188-98
All:	10 reference(s)