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Gene Expression Data
Assay Details
Assay
Reference: J:108109 Oxburgh L, et al., TGFbeta superfamily signals are required for morphogenesis of the kidney mesenchyme progenitor population. Development. 2004 Sep;131(18):4593-605
Assay type: RNA in situ
MGI Accession ID: MGI:3654446
Gene symbol: Aldh1a2
Gene name: aldehyde dehydrogenase family 1, subfamily A2
Results
Specimen 4G, 4G': embryonic day 14.5 (more )
Note: Fig. 4G' is a higher magnification of Fig. 4G.
Structure Level Pattern Image Note
TS22: mesenchyme of metanephros Present 4G' , 4G
Specimen 4H, 4H': embryonic day 14.5; Bmp7tm6(cre)Rob/Bmp7+, Smad4tm1Rob/Smad4tm1.1Rob (more )
Note: Conditional mutant. Fig. 4H' is a higher magnification of Fig. 4H.
Structure Level Pattern Image Note
TS22: mesenchyme of metanephros Present Regionally restricted 4H , 4H' Expression was detected in cells with characteristics of peripheral stroma in the expanded cortical region of the mutant kidneys.
TS22: renal cortex Present Regionally restricted 4H , 4H' Expression was detected in cells with characteristics of peripheral stroma in the expanded cortical region of the mutant kidneys.
Specimen 4K: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: mesenchyme of metanephros Present 4K
Specimen 4L: embryonic day 14.5; Bmp7tm6(cre)Rob/Bmp7+, Smad4tm1Rob/Smad4tm1.1Rob (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS22: mesenchyme of metanephros Present Regionally restricted 4L Expression was detected in cells with characteristics of peripheral stroma in the expanded cortical region of the mutant kidneys.
TS22: renal cortex Present Regionally restricted 4L Expression was detected in cells with characteristics of peripheral stroma in the expanded cortical region of the mutant kidneys.
Specimen 4O: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: mesenchyme of metanephros Present 4O
Specimen 4P: embryonic day 16.5; Bmp7tm6(cre)Rob/Bmp7+, Smad4tm1Rob/Smad4tm1.1Rob (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS24: mesenchyme of metanephros Present Regionally restricted 4P Expression was detected in cells with characteristics of peripheral stroma in the expanded cortical region of the mutant kidneys.
TS24: renal cortex Present Regionally restricted 4P Expression was detected in cells with characteristics of peripheral stroma in the expanded cortical region of the mutant kidneys.
Specimen 5E: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: metanephric mesenchyme Present Regionally restricted 5E Expression was detected in the stroma but was excluded from condensates around the ureteric bud tips.
Specimen 5F: embryonic day 11.5; Bmp7tm6(cre)Rob/Bmp7+, Smad4tm1Rob/Smad4tm1.1Rob (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: metanephric mesenchyme Present Regionally restricted 5F Expression was detected in the stroma but was excluded from condensates around the ureteric bud tips as in wild type.
Specimen 5M: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: mesenchyme of metanephros Present Regionally restricted 5M Expression was detected in the stroma but was absent from the nephrogenic mesenchyme.
TS20: primitive collecting duct Absent 5M
Specimen 5N: embryonic day 12.5; Bmp7tm6(cre)Rob/Bmp7+, Smad4tm1Rob/Smad4tm1.1Rob (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS20: mesenchyme of metanephros Present Regionally restricted 5N Expression was spread throughout the majority of the mesenchyme, and is excluded from the limited nephrogenic mesenchyme.
TS20: primitive collecting duct Absent 5N
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory