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Gene Expression Data
Assay Details
Assay
Reference: J:87222 Morkel M, et al., Beta-catenin regulates Cripto- and Wnt3-dependent gene expression programs in mouse axis and mesoderm formation. Development. 2003 Dec;130(25):6283-94
Assay type: RNA in situ
MGI Accession ID: MGI:3653925
Gene symbol: Nanog
Gene name: Nanog homeobox
Probe: Nanog probe1
Assay notes: The Beta-/- mutant allele was not detailed; the authors may have used Ctnnb1<tm1Wbm> or Ctnnb1<tm2Wbm>.
Results
Specimen 2K: embryonic day 6.0 (more )
Structure Level Pattern Image Note
TS8: epiblast Present Regionally restricted 2K Expression was detected in proximal embryonic ectoderm.

Specimen 2L: embryonic day 6.5 (more )
Structure Level Pattern Image Note
TS9: embryo ectoderm Present Regionally restricted 2L Expression was detected in distal and posterior embryonic ectoderm.

Specimen 2M: embryonic day 6.5 (more )
Structure Level Pattern Image Note
TS9: embryo ectoderm Present Regionally restricted 2M Expression was detected in distal and posterior embryonic ectoderm.

Specimen 2N: embryonic day 6.5; Ctnnb1tm1Wbm/Ctnnb1tm1Wbm (more )
Structure Level Pattern Image Note
TS9: embryo ectoderm Absent 2N Expression was absent from distal and posterior embryonic ectoderm.

Specimen 4G: embryonic day 6.5 (more )
Structure Level Pattern Image Note
TS9: embryo ectoderm Present Regionally restricted 4G Expression was detected in posterior ectoderm.

Specimen 4H: embryonic day 6.5; Ctnnb1tm1Mmt/Ctnnb1tm1Mmt (more )
Structure Level Pattern Image Note
TS9: embryo ectoderm Present Regionally restricted 4H There was loss of assymetrical expression pattern in the mutant.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory