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Gene Expression Data
Assay Details
Assay
Reference: J:86170 Menke DB, et al., Sexual differentiation of germ cells in XX mouse gonads occurs in an anterior-to-posterior wave. Dev Biol. 2003 Oct 15;262(2):303-12
Assay type: RNA in situ
MGI Accession ID: MGI:3652405
Gene symbol: Adamts19
Gene name: ADAM metallopeptidase with thrombospondin type 1 motif 19
Probe: Adamts19 cDNA1
Probe preparation: labelled with digoxigenin RNA
Results
Specimen 4A: embryonic day 12.0 (more )
Note: 24 tail somites.
Structure Level Pattern Image Note
TS20: ovary Present Regionally restricted 4A Expression at the anterior tip had spread along the ventral aspect of the genital ridge toward the posterior pole, but there was still an anterior bias in the XX gonad.
Specimen 4B: embryonic day 12.0 (more )
Note: 24 tail somites.
Structure Level Pattern Image Note
TS20: testis Weak Regionally restricted 4B Expression at the anterior tip was lost or greatly reduced in XY gonads.
Specimen not shown: embryonic day 11.5 (more )
Note: 19 tail somites.
Structure Level Pattern Image Note
TS19: gonad Present Regionally restricted Expression was detected at the anterior tips.
Specimen not shown: embryonic day 11.5 (more )
Note: 19 tail somites.
Structure Level Pattern Image Note
TS19: gonad Present Regionally restricted Expression was detected at the anterior tips.
Specimen 6J: embryonic day 14.5 (more )
Note: XYZal Mildly feminized.
Structure Level Pattern Image Note
TS22: gonad Present Regionally restricted 6J Expression was present in the feminized regions but was excluded from the masculinized regions. The expression level was variable in the mildly feminized ovotestes.
Specimen 6K: embryonic day 14.5 (more )
Note: XYZal Severely feminized.
Structure Level Pattern Image Note
TS22: gonad Present Regionally restricted 6K Expression was strong in the feminized regions but was excluded from the masculinized regions of severely sex reversed gonads.
Specimen 6L: embryonic day 14.5 (more )
Note: XYZal Sex reversed.
Structure Level Pattern Image Note
TS22: gonad Present Regionally restricted 6L Expression was strong in the feminized regions but was excluded from the masculinized regions of fully sex reversed gonads.
Specimen not shown: embryonic day 12.5 (more )
Note: 30 tail somites.
Structure Level Pattern Image Note
TS20: testis Absent
Specimen not shown: embryonic day 12.5 (more )
Note: 30 tail somites.
Structure Level Pattern Image Note
TS20: ovary Present
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory