Slc7a8 In situ reporter (knock in) Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:101679 Deltagen Inc, NIH initiative supporting placement of Deltagen, Inc. mice into public repositories. MGI Direct Data Submission. 2005;
Assay type:	In situ reporter (knock in)
MGI Accession ID:	MGI:3639245
Gene symbol:	Slc7a8
Gene name:	solute carrier family 7 (cationic amino acid transporter, y+ system), member 8

Reporter:	lacZ
	Direct Detection

Results

Specimen Mouse 298215: postnatal day 58; Slc7a8^tm1Dgen/Slc7a8⁺ (more

)

Structure	Level	Note
TS28: cervix uteri	Absent
TS28: adenohypophysis pars anterior	Moderate	There is scattered expression in the pars distalis.
TS28: cerebellum	Very strong	Expression is frequently seen in the cerebellum.
TS28: ovary	Moderate	There is scattered expression in the ovary.
TS28: brain	Very strong	Expression is frequently seen in the brain.
TS28: brainstem	Very strong	There is scattered expression in the brainstem.
TS28: uterus	Absent
TS28: telencephalon	Very strong	Expression is frequently seen in the cerebrum.
TS28: bladder	Absent

Specimen Mouse 308799: postnatal day 52; Slc7a8^tm1Dgen/Slc7a8⁺ (more

)

Structure	Level	Pattern	Note
TS28: lens	Very strong		Expression is frequently seen in the lens.
TS28: pigmented retinal epithelium	Strong		There is scattered expression in the pigment layer.
TS28: spinal cord dorsal horn	Weak		There is occasional staining in the dorsal horns.
TS28: amygdala	Very strong		Expression is frequently seen in the amygdala.
TS28: metanephros	Present		There is very strong, scattered expression in the kidney. In addition, there is strong, scattered expression in the blood vessels of the kidney.
TS28: aorta	Absent
TS28: renal medulla	Strong		There is occasional staining in the medulla.
TS28: thymus	Strong		There is occasional staining in the thymus.
TS28: retina ganglion cell layer	Strong		There is scattered expression in the ganglion cell layer.
TS28: seminiferous tubule	Strong		There is occasional staining in the seminiferous tubules.
TS28: ciliary body	Strong		There is scattered expression in the ciliary body.
TS28: hypothalamus	Strong		There is occasional staining in the hypothalamus.
TS28: hippocampus	Very strong		Expression is frequently seen in the hippocampus.
TS28: islets of Langerhans	Strong		Expression is frequently seen in the islets of Langerhans.
TS28: pancreatic acinus	Strong		Expression is frequently seen in the acini.
TS28: cerebral cortex	Very strong		Expression is present in practically all cells of the cortex.
TS28: caudate-putamen	Very strong		There is scattered expression in the caudate-putamen.
TS28: thalamus	Very strong		Expression is frequently seen in the thalamus.
TS28: cerebellum molecular layer	Strong		There is scattered expression in the molecular layer.
TS28: spinal cord ventral horn	Strong		There is occasional staining in the ventral horns.
TS28: telencephalon	Present	Regionally restricted	Very strong expression is frequently seen in the cerebrum. Strong expression is frequently seen in the choroid plexus of the cerebrum.
TS28: prostate epithelium	Weak		There is occasional staining in the epithelium.
TS28: brainstem	Strong		There is scattered expression in the brainstem.
TS28: cornea	Very strong		There is occasional staining in the cornea.
TS28: spinal cord	Strong	Regionally restricted	There is scattered expression in the dorsal root ganglion.
TS28: parathyroid gland	Very strong		There is scattered expression in the parathyroid gland.
TS28: interstitium of the testis	Very strong		Expression is frequently seen in the interstitium.
TS28: heart	Absent
TS28: retina inner nuclear layer	Strong		There is scattered expression in the inner nuclear layer.
TS28: blood vessel	Strong	Regionally restricted	There is scattered expression in the blood vessels of the kidney.
TS28: cerebellum Purkinje cell layer	Very strong		Expression is present in practically all cells of the Purkinje layer.
TS28: dorsal root ganglion	Strong	Regionally restricted	There is scattered expression in the dorsal root ganglion.
TS28: choroid plexus	Strong	Regionally restricted	Expression is frequently seen in the choroid plexus of the cerebrum.
TS28: liver	Absent
TS28: retina	Strong		There is occasional staining in the retina.
TS28: renal cortex	Very strong		There is scattered expression in the cortex.
TS28: adrenal cortex	Absent
TS28: thyroid gland	Absent
TS28: bone marrow	Absent
TS28: spleen	Absent
TS28: lymph node	Absent
TS28: skin	Absent
TS28: skeletal muscle	Absent
TS28: lung	Absent
TS28: bladder	Absent

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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