Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Tnks2tm1.1Yjc
Name:	tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2; targeted mutation 1.1, Y Jeffrey Chiang
MGI ID:	MGI:3621924
Synonyms:	Tank2-
Gene:	Tnks2  Location: Chr19:36811632-36870877 bp, + strand  Genetic Position: Chr19, 31.96 cM
Alliance:	Tnks2tm1.1Yjc page

Germline Transmission:	Earliest citation of germline transmission: J:106918
Parent Cell Line:	CJ7 (ES Cell)
Strain of Origin:	129S1/Sv-Oca2+ Tyr+ Kitl+

Allele Type:    Targeted (Null/knockout) Mutation:    Intragenic deletion     Exon 1 was removed via cre-mediated excision. RT-PCR failed to detect transcript in mutants. (J:106918)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Tnks2 Mutation:	48 strains or lines available

Original:	J:106918 Chiang YJ, et al., Generation and characterization of telomere length maintenance in tankyrase 2-deficient mice. Mol Cell Biol. 2006 Mar;26(6):2037-43
All:	4 reference(s)