Tg(HLA-B/H2-K)1Chmb
Transgene Detail
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| Symbol: |
Tg(HLA-B/H2-K)1Chmb |
| Name: |
transgene insertion 1, Jeffrey W Chamberlain |
| MGI ID: |
MGI:2447799 |
| Synonyms: |
HLA-B7hyb |
| Transgene: |
Tg(HLA-B/H2-K)1Chmb Location: unknown
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| Alliance: |
Tg(HLA-B/H2-K)1Chmb page
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| Strain of Origin: |
(C57BL/6 x SJL)F2
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| Transgene Type: |
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Transgenic (Inserted expressed sequence) |
| Mutation: |
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Insertion
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Tg(HLA-B/H2-K)1Chmb expresses
1 gene
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Mutation details: The transgene consists of human genomic HLA-B7 sequences spanning 5' flanking DNA and exons 1-3 fused to mouse genomic H2-K sequences spanning exona 4-8 and 3' flanking DNA.
(J:80678)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:80678 Borenstein SH, et al., CD8+ T cells are necessary for recognition of allelic, but not locus-mismatched or xeno-, HLA class I transplantation antigens. J Immunol. 2000 Sep 1;165(5):2341-53 |
| All: |
2 reference(s) |
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Analysis Tools
