Tg(H2-K-Stat5b)1Wjl
Transgene Detail
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| Symbol: |
Tg(H2-K-Stat5b)1Wjl |
| Name: |
transgene insertion 1, Warren J Leonard |
| MGI ID: |
MGI:2448073 |
| Synonyms: |
TG1 |
| Transgene: |
Tg(H2-K-Stat5b)1Wjl Location: unknown
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| Alliance: |
Tg(H2-K-Stat5b)1Wjl page
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| Transgene Type: |
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Transgenic (Inserted expressed sequence) |
| Mutation: |
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Insertion
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Tg(H2-K-Stat5b)1Wjl expresses
1 gene
Transgene expresses:
| Organism |
Expressed Gene |
Note |
| mouse |
Stat5b (MGI:103035) |
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Mutation details: The transgenic construct contained sequence encoding Stat5b driven by a H2-K promoter and followed by an IgH enhancer. Stat5b overexpression was verified in the thymus and spleen by Western blot analysis. Western blot analysis using a an anti-phospho-Stat5b antibody showed that the transgenic protein was phosphorylated upon Il2 stimulation.
(J:80897)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:80897 Kelly J, et al., A role for stat5 in CD8(+) T cell homeostasis. J Immunol. 2003 Jan 1;170(1):210-7 |
| All: |
5 reference(s) |
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Analysis Tools
