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Gene Expression Data
Assay Details
Assay
Reference: J:103780 Maurer ME, et al., Endocytosis of megalin by visceral endoderm cells requires the Dab2 adaptor protein. J Cell Sci. 2005 Nov 15;118(Pt 22):5345-55
Assay type: Immunohistochemistry
MGI Accession ID: MGI:3617842
Gene symbol: Eea1
Gene name: early endosome antigen 1
Antibody: anti-EEA1
Detection system: Secondary antibody coupled to Alexa Fluor
Results
Specimen 2B +/?: embryonic day 6.5; Dab2tm1.1Cpr/Dab2+ (more )
Note: Littermate control; embryos were either +/+ or +/-. Double labeled: red - Eea1; green - Dab2 (assay MGI:3617839).
Structure Level Pattern Image Note
TS9: extraembryonic visceral endoderm Present Regionally restricted 2B Expression is in early endosomes.
Specimen 2D -/-: embryonic day 6.5; Dab2tm1.1Cpr/Dab2tm1.1Cpr (more )
Note: Double labeled: red - Eea1; green - Dab2 (assay MGI:3617839).
Structure Level Pattern Image Note
TS9: extraembryonic visceral endoderm Weak Regionally restricted 2D Expression in early endosomes is reduced in this mutant.
Specimen 2F +/?: embryonic day 6.5; Dab2tm1.1Cpr/Dab2+ (more )
Note: Littermate control; embryos were either +/+ or +/-. Double labeled: red - Eea1; green - Lrp2 (megalin; assay MGI:3617845).
Structure Level Pattern Image Note
TS9: extraembryonic visceral endoderm Present 2F Expression is in early endosomes.
Specimen 2H -/-: embryonic day 6.5; Dab2tm1.1Cpr/Dab2tm1.1Cpr (more )
Note: Double labeled: red - Eea1; green - Lrp2 (megalin; assay MGI:3617845).
Structure Level Pattern Image Note
TS9: extraembryonic visceral endoderm Weak 2H Expression in early endosomes is reduced in this mutant.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory