Gene Expression Data
Assay Details
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Assay
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Reference:
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J:104492
Huang KM, et al., Xcat, a novel mouse model for Nance-Horan syndrome inhibits expression of the cytoplasmic-targeted Nhs1 isoform. Hum Mol Genet. 2006 Jan 15;15(2):319-27
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:3615266
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Gene symbol:
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Mip
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Gene name:
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major intrinsic protein of lens fiber
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Antibody:
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anti-aquaporin O/MIP
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Detection system:
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Secondary antibody coupled to Alexa Fluor 488
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Assay notes:
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After sectioning, slides were fixed with ice cold 1:1 acetone:methanol.
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Results
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Specimen
4G:
postnatal newborn; NhsXcat/Nhs +
(more  )
Note: This mutation is an X linked dominant; it is possible this specimen was a homozygous female or a mutant male.
Specimen
4G:
(close  )
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Genetic Background:
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involves: C57BL/6 * DBA/2 * T STOCK
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Mutant Allele(s):
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NhsXcat/Nhs+
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Age:
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postnatal newborn
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Fresh Frozen
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Embedding:
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Cryosection
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Note:
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This mutation is an X linked dominant; it is possible this specimen was a homozygous female or a mutant male.
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| Structure |
Level |
Pattern |
Image |
Note |
| TS27: lens |
Strong |
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4G
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Analysis Tools
