About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:104158 Alanentalo T, et al., Cloning and analysis of Nkx6.3 during CNS and gastrointestinal development. Gene Expr Patterns. 2006 Jan;6(2):162-70
Assay type: RNA in situ
MGI Accession ID: MGI:3614651
Gene symbol: Nkx6-3
Gene name: NK6 homeobox 3
Probe: Nkx6-3 cDNA1
Probe preparation: Antisense RNA
Results
Specimen Not Shown: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: hindbrain Present Regionally restricted Expression is in a small population of post-mitotic neurons in the ventral hindbrain.
Specimen 3A: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: hindbrain Present Regionally restricted 3A Expression is in the caudal hindbrain.
Specimen 3B: embryonic day 11.5 (more )
Note: Flat mount.
Structure Level Pattern Image Note
TS19: hindbrain Present Regionally restricted 3B Expression is extending from the boundary of rhombomere 5/6 to the hindbrain/spinal cord boundary.
Specimen 3C: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: hindbrain Present Regionally restricted 3C Expression is in the caudal hindbrain.
Specimen 3D: embryonic day 12.5 (more )
Note: Double labeled: green - Nkx6-3; red - Lhx3 (assay MGI:3615109).
Structure Level Pattern Image Note
TS20: hindbrain Present Regionally restricted 3D Expression is in the caudal hindbrain.
Specimen 3E: embryonic day 12.5 (more )
Note: Double labeled: green - Nkx6-3; red - Vsx2 (Chx10; assay MGI:3615114).
Structure Level Pattern Image Note
TS20: hindbrain Present Regionally restricted 3E Expression is in the caudal hindbrain.
Specimen 3F: embryonic day 12.5 (more )
Note: Double labeled: green - Nkx6-3; red - Nkx6-1 (assay MGI:3614671).
Structure Level Pattern Image Note
TS20: hindbrain Present Regionally restricted 3F Expression is in the caudal hindbrain.
Specimen 3G: embryonic day 12.5 (more )
Note: Double labeled: green - Nkx6-3; red - Nkx6-2 (assay MGI:3614855).
Structure Level Pattern Image Note
TS20: hindbrain Present Regionally restricted 3G Expression is in the caudal hindbrain.
Specimen 3L: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: hindbrain Present Regionally restricted 3L Expression is in the caudal hindbrain.
Specimen 3M: embryonic day 12.5; Nkx6-1tm1Jlr/Nkx6-1tm1Jlr (more )
Structure Level Pattern Image Note
TS20: hindbrain Present Regionally restricted 3M The region of expression is in the caudal hindbrain is reduced in this mutant.
Specimen 3N: embryonic day 12.5; Nkx6-2tm1Ercs/Nkx6-2tm1Ercs (more )
Structure Level Pattern Image Note
TS20: hindbrain Present Regionally restricted 3N Expression is in the caudal hindbrain. Expression in this mutant is the same as in wild-type embryos.
Specimen 4C: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: foregut-midgut junction Absent 4C Expression is absent in the pancreatic epithelium, stomach and duodenal endoderm.
Specimen 4F: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: foregut-midgut junction Present Regionally restricted 4F Expression is in the duodenal region and is absent in the pancreatic epithelium.
TS17: pancreas primordium Absent 4F Expression is in the duodenal region and is absent in the pancreatic epithelium.
TS17: stomach Present Regionally restricted 4F Expression is caudal.
Specimen 4I: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: foregut-midgut junction Present Regionally restricted 4I Expression is in the duodenal region and is absent in the pancreatic epithelium.
TS17: pancreas primordium Absent 4I Expression is in the duodenal region and is absent in the pancreatic epithelium.
TS17: stomach Present Regionally restricted 4I Expression is caudal.
Specimen 4L: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: pancreas Absent 4L
Specimen 5C: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: stomach glandular region epithelium Present Regionally restricted 5C Expression is in the caudal stomach.
TS20: foregut duodenum Present Regionally restricted 5C Expression is in the anterior portion.
Specimen 5F,I: embryonic day 16.5 (more )
Note: (G)-(I) shows high magnification of the glandular stomach and duodenum (inset) seen in (D)-(F).
Structure Level Pattern Image Note
TS24: stomach glandular region epithelium Present 5I , 5F
TS24: duodenum Present Regionally restricted 5F Expression is in the proximal duodenum.
Specimen 5I inset: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: duodenum Present Regionally restricted 5I inset Expression is in the proximal duodenum.
Specimen 5L: postnatal newborn (more )
Structure Level Pattern Image Note
TS27: stomach Present Regionally restricted 5L Expression is at the base of the gastric units.
Specimen 5O: postnatal adult (more )
Structure Level Pattern Image Note
TS28: stomach Present Regionally restricted 5O Expression is at the base of the gasrtic units.
Specimen 6C: postnatal newborn (more )
Structure Level Pattern Image Note
TS27: stomach Present Regionally restricted 6C Expression is predominantly in the crypts of the gastric units.
Specimen S1R: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: neural tube basal columns Absent S1_R
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory