Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	P2ry2tm1Bhk
Name:	purinergic receptor P2Y, G-protein coupled 2; targeted mutation 1, Beverly Koller
MGI ID:	MGI:3613160
Synonyms:	P2ry2tm1Bouc, P2Y2-, P2Y2-R-
Gene:	P2ry2  Location: Chr7:100645775-100661260 bp, - strand  Genetic Position: Chr7, 54.47 cM, cytoband F1
Alliance:	P2ry2tm1Bhk page

Germline Transmission:	Earliest citation of germline transmission: J:57617
Parent Cell Line:	E14TG2a (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A neomycin selection cassette replaced a genomic fragment corresponding to base pairs 552 - 1149 of the published cDNA. Northern blot analysis on RNA derived from kidney of homozygous mice confirmed that no detectable transcript is expressed from this allele. (J:57617)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any P2ry2 Mutation:	18 strains or lines available

Original:	J:57617 Homolya L, et al., Nucleotide-regulated calcium signaling in lung fibroblasts and epithelial cells from normal and P2Y(2) receptor (-/-) mice. J Biol Chem. 1999 Sep 10;274(37):26454-60
All:	67 reference(s)