Summary | Transgene origin | Transgene description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Tg(Fabp4-Agt)1Mte
Name:	transgene insertion 1, Michele Teboul
MGI ID:	MGI:3608885
Transgene:	Tg(Fabp4-Agt)1Mte  Location: unknown
Alliance:	Tg(Fabp4-Agt)1Mte page

Strain of Origin:

(C57BL/6 x DBA/2)

Transgene Type:    Transgenic (Inserted expressed sequence) Mutation:    Insertion   Tg(Fabp4-Agt)1Mte expresses 1 gene Transgene expresses: Organism Expressed Gene Homolog in Mouse Note rat Agt (24179) Agt  (MGI:87963)   Mutation details: This transgene overexpresses the rat Agt gene under the control of the adipocyte-specific Fabp4 promoter. Northern blot and RT-PCR analysis indicates specific Agt expression in adipose tissue with small amounts of mRNA detected in muscle and heart and none in liver or kidney. Several lines were made, with this line (Line 1) expressing the lowest levels of Agt. (J:73163)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available

Original:	J:73163 Massiera F, et al., Adipose angiotensinogen is involved in adipose tissue growth and blood pressure regulation. FASEB J. 2001 Dec;15(14):2727-9
All:	2 reference(s)