Tg(CD2-TRAV24-TRAJ18/Tcra-C)1Rmd
Transgene Detail
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| Symbol: |
Tg(CD2-TRAV24-TRAJ18/Tcra-C)1Rmd |
| Name: |
transgene insertion 1, Hugh Robson MacDonald |
| MGI ID: |
MGI:3607139 |
| Transgene: |
Tg(CD2-TRAV24-TRAJ18/Tcra-C)1Rmd Location: unknown
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| Alliance: |
Tg(CD2-TRAV24-TRAJ18/Tcra-C)1Rmd page
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| Strain of Origin: |
C57BL/6 x DBA/2
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| Transgene Type: |
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Transgenic (Inserted expressed sequence) |
| Mutation: |
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Insertion
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Tg(CD2-TRAV24-TRAJ18/Tcra-C)1Rmd expresses
1 gene
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Mutation details: The gene segment from human TCR alpha receptor V24 (TRAV24) to TCR alpha receptor JQ (TRAJ18) was fused with the mouse Tcra-C and placed under the control of the human CD2 enhancer promoter. This construct was injected into C57BL/6 x DBA/2 fertilized eggs. Five founders were identified. Founders 1-4 expressed the transgene at a high frequency whereas founder 5 expressed the transgene at a low frequency.
(J:82014)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:82014 Capone M, et al., Human invariant V alpha 24-J alpha Q TCR supports the development of CD1d-dependent NK1.1+ and NK1.1- T cells in transgenic mice. J Immunol. 2003 Mar 1;170(5):2390-8 |
| All: |
3 reference(s) |
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Analysis Tools
