Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | Notes | References

Symbol:	Esrratm1Dgen
Name:	estrogen related receptor, alpha; targeted mutation 1, Deltagen
MGI ID:	MGI:3604552
Gene:	Esrra  Location: Chr19:6888345-6899182 bp, - strand  Genetic Position: Chr19, 5.08 cM
Alliance:	Esrratm1Dgen page

Mutant Cell Line:	8363
Germline Transmission:	Earliest citation of germline transmission: J:101679
Parent Cell Line:	E14 (ES Cell)
Strain of Origin:	129P2/OlaHsd
Project Collection:	Deltagen

Allele Type:    Targeted (Null/knockout, Reporter) Mutation:    Disruption caused by insertion of vector   Mutation details: A bacterial lacZ gene was inserted into the gene such that the endogenous gene promoter drives expression of beta-galactosidase. While RT-PCR analysis detects a low level of gene transcript in cerebellum, heart, thymus, skin, gallbladder, pituitary gland, skeletal muscle, tongue and stomach, beta-galactosidase expression from this allele is detectable in most organs examined. Most striking expression was detected in the central nervous system, heart and kidney.

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:

92 assay results

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Esrra Mutation:	25 strains or lines available

Original:	J:101679 Deltagen Inc, NIH initiative supporting placement of Deltagen, Inc. mice into public repositories. MGI Direct Data Submission. 2005;
All:	6 reference(s)