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Gene Expression Data
Assay Details
Assay
Reference: J:51745 Glinka A, et al., Dickkopf-1 is a member of a new family of secreted proteins and functions in head induction. Nature. 1998 Jan 22;391(6665):357-62
Assay type: RNA in situ
MGI Accession ID: MGI:3603143
Gene symbol: Dkk1
Gene name: dickkopf WNT signaling pathway inhibitor 1
Probe: mdkk-1 cDNA
Probe preparation: Antisense RNA
Results
Specimen 2h: embryonic day 6.5 (more )
Structure Level Pattern Image Note
TS9: embryo mesoderm Present Regionally restricted 2h Expression is present in a subpopulation of cells that will form the extraembryonic and head-fold mesoderm. These cells are adjacent to the embryonic/extraembryonic junction.

Specimen 2i: embryonic day 7.0 (more )
Structure Level Pattern Image Note
TS10: embryo mesoderm Present Regionally restricted 2i Expression is restricted to head mesoderm.

Specimen 2j: embryonic day 7.0 (more )
Structure Level Pattern Image Note
TS10: embryo mesoderm Present Regionally restricted 2j Expression is restricted to head mesoderm.
TS10: primitive streak Absent 2j

Specimen 2k: embryonic day 8.0 (more )
Structure Level Pattern Image Note
TS12: embryo endoderm Strong Regionally restricted 2k Expression is present in foregut endoderm cells adjacent to the head fold.
TS12: head mesenchyme Present Regionally restricted 2k Only a few head mesodermal cells continue to express.
TS12: future prosencephalon Present Regionally restricted 2k Expression is present in a small rostral domain in the diencephalon.
TS12: future spinal cord Present 2k
TS12: embryo mesenchyme Weak Regionally restricted 2k Expression is present in posterior primitive streak mesoderm.

Specimen Not shown: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: somite Present Expression is present in developing somites.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory