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mdkk-1 cDNA Probe Detail
Nucleotide
Probe/Clone
  • Name
    mdkk-1 cDNA
  • Sequence Type
    cDNA
  • ID
    MGI:1329444
  • Region Covered
    includes portion of coding region
Source
  • Species
    mouse, laboratory
  • Age
    embryonic day 9.0
  • Tissue
    embryo
Genes
Dkk1 dickkopf WNT signaling pathway inhibitor 1
Expression
  • Assay Results
    163
Sequences
AF030433 (GenBank | EMBL | ENA | DDBJ | MGI Sequence Detail)
References
J:51745 Glinka A, et al., Dickkopf-1 is a member of a new family of secreted proteins and functions in head induction. Nature. 1998 Jan 22;391(6665):357-62
J:57798 Monaghan AP, et al., Dickkopf genes are co-ordinately expressed in mesodermal lineages. Mech Dev. 1999 Sep;87(1-2):45-56
J:58627 Grotewold L, et al., Expression pattern of Dkk-1 during mouse limb development. Mech Dev. 1999 Dec;89(1-2):151-3
J:67152 Perea-Gomez A, et al., Otx2 is required for visceral endoderm movement and for the restriction of posterior signals in the epiblast of the mouse embryo. Development. 2001 Mar;128(5):753-65
J:74631 Tian E, et al., Otx2 is required to respond to signals from anterior neural ridge for forebrain specification. Dev Biol. 2002 Feb 15;242(2):204-23
J:79899 Grotewold L, et al., The Fused toes (Ft) mouse mutation causes anteroposterior and dorsoventral polydactyly. Dev Biol. 2002 Nov 1;251(1):129-41
J:92327 Adamska M, et al., En1 and Wnt7a interact with Dkk1 during limb development in the mouse. Dev Biol. 2004 Aug 1;272(1):134-44
J:146657 Witte F, et al., Comprehensive expression analysis of all Wnt genes and their major secreted antagonists during mouse limb development and cartilage differentiation. Gene Expr Patterns. 2009 Apr;9(4):215-23
J:160259 Lieven O, et al., The regulation of Dkk1 expression during embryonic development. Dev Biol. 2010 Apr 15;340(2):256-68
J:192194 Tortelote GG, et al., Wnt3 function in the epiblast is required for the maintenance but not the initiation of gastrulation in mice. Dev Biol. 2013 Feb 1;374(1):164-73
J:236404 Minocha S, et al., Epiblast-specific loss of HCF-1 leads to failure in anterior-posterior axis specification. Dev Biol. 2016 Oct 1;418(1):75-88

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/21/2024
MGI 6.23
The Jackson Laboratory