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Gene Expression Data
Assay Details
Assay
Reference: J:73669 Stottmann RW, et al., The BMP antagonists Chordin and Noggin have essential but redundant roles in mouse mandibular outgrowth. Dev Biol. 2001 Dec 15;240(2):457-73
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:3583825
Gene symbol: Nog
Gene name: noggin
Reporter: lacZ
Direct Detection
Results
Specimen 1A: embryonic day 8.5; Nogtm1Amc/Nog+ (more )
Structure Level Pattern Image Note
TS13: 1st branchial arch mesenchyme Present Regionally restricted 1A Expression is detected in a punctate pattern in the initial swelling (mesenchyme) of the 1st branchial arch suggesting migrating neural crest cells.
TS13: migrating neural crest Present Regionally restricted 1A Expression is detected in a punctate pattern in the initial swelling (mesenchyme) of the 1st branchial arch suggesting migrating neural crest cells.
Specimen 1B: embryonic day 9.5; Nogtm1Amc/Nog+ (more )
Structure Level Pattern Image Note
TS15: 1st branchial arch mandibular component mesenchyme Present Regionally restricted 1B Expression is detected in a punctate pattern in the initial swelling (mesenchyme) of the 1st branchial arch suggesting migrating neural crest cells.
TS15: migrating neural crest Present Regionally restricted 1B Expression is detected in a punctate pattern in the initial swelling (mesenchyme) of the 1st branchial arch suggesting migrating neural crest cells.
TS15: neural tube Present Regionally restricted 1B Expression detected in the dorsal neural tube in a rhombomere specific pattern.
TS15: 1st branchial arch mandibular component ectoderm Present Regionally restricted 1B Expression detected in the pharyngeal/caudal mandibular ectoderm.
Specimen 1G: embryonic day 10.5; Nogtm1Amc/Nog+ (more )
Structure Level Pattern Image Note
TS17: 1st branchial arch mandibular component ectoderm Weak Single cells 1G Expression detected in individual cells of the oral epithelium.
TS17: 1st branchial arch Present Regionally restricted 1G Expression detected in Meckel's cartilage.
Specimen 1H: embryonic day 11.5; Nogtm1Amc/Nog+ (more )
Structure Level Pattern Image Note
TS19: 1st branchial groove epithelium Weak Single cells 1H Expression detected in individual cells of the oral epithelium.
TS19: 1st branchial arch Strong Regionally restricted 1H High expression is detected in the deep Mesenchyme.
Specimen 7A: embryonic day 10.5; Nogtm1Amc/Nog+ (more )
Structure Level Pattern Image Note
TS17: embryo Present 7A
Specimen 7B: embryonic day 10.5; Nogtm1Amc/Nogtm1Amc (more )
Structure Level Pattern Image Note
TS17: embryo Strong Regionally restricted 7B Higher levels of expression compared with heterozygous littermates.
TS17: 1st branchial arch mesenchyme derived from neural crest Strong 7B
Specimen 7C: embryonic day 11.5; Chrdtm1Emdr/Chrdtm1Emdr, Nogtm1Amc/Nogtm1Amc (more )
Structure Level Pattern Image Note
TS19: embryo Very strong Regionally restricted 7C
TS19: branchial arch mesenchyme derived from neural crest Very strong 7C
Specimen 7D: embryonic day 10.5; Nogtm1Amc/Nog+ (more )
Structure Level Pattern Image Note
TS17: 1st branchial arch Present 7D
Specimen 7E: embryonic day 10.5; Nogtm1Amc/Nogtm1Amc (more )
Structure Level Pattern Image Note
TS17: 1st branchial arch Strong 7E
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/23/2024
MGI 6.23 		The Jackson Laboratory